Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.52 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344717 | 0.94 | FAAH (0.61) | FAAHASAH1PSMB5CASP2MEN1 | |
| SCHEMBL28125168 | 0.92 | FAAH (0.64) | FAAHASAH1CASP2MEN1MAPK1 | |
| SCHEMBL28713712 | 0.92 | FAAH (0.64) | FAAHASAH1CASP2MEN1MAPK1 | |
| SCHEMBL4358198 | 0.92 | FAAH (0.64) | FAAHASAH1CASP2MEN1MAPK1 | |
| SCHEMBL27546913 | 0.92 | FAAH (0.64) | FAAHASAH1CASP2MEN1MAPK1 | |
| SCHEMBL28954298 | 0.86 | CASP2 (0.48) | FAAHASAH1PSMB5CASP2HPGD | |
| SCHEMBL18848447 | 0.85 | FAAH (0.50) | FAAHASAH1PSMB5CASP2MEN1 | |
| Oxirane SCHEMBL4445778 | 0.84 | FAAH (0.55) | FAAHASAH1CASP2MEN1MAPK1 | |
| SCHEMBL3914202 | 0.83 | HPGD (0.54) | FAAHASAH1PSMB5CASP2MEN1 | |
| SCHEMBL6553246 | 0.82 | EPHX2 (0.61) | FAAHMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255308-A | A DISPERSION COMPRISING A BINDER OF A METHYL METHACRYLATE POLYMER, A DISPERSANT OF AN ACRYLIC TERPOLYMER, AND A GRAFT POLYMER OF THE TWO; FINISHES FOR CARS AND TRUCKS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-10 | — | — | US | disclosed |