Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210392 | 1.00 | CDC7 (0.30) | CDC7PKN1PKN2 | |
| SCHEMBL3210387 | 1.00 | CDC7 (0.30) | CDC7PKN1PKN2 | |
| SCHEMBL2316760 | 0.74 | ALDH1A1 (0.47) | CDC7 | |
| SCHEMBL1737418 | 0.72 | IDO1 (0.34) | — | |
| SCHEMBL947045 | 0.64 | — | — | |
| SCHEMBL25431616 | 0.62 | IDO1 (0.35) | — | |
| SCHEMBL18366014 | 0.62 | CRBN (0.37) | — | |
| SCHEMBL3933129 | 0.60 | — | — | |
| SCHEMBL20155054 | 0.58 | MAP2K1 (0.42) | — | |
| SCHEMBL19359650 | 0.58 | MAP2K1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612088-B2 | Heterocyclic compounds and their use as aldosterone synthase inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2009-11-03 | — | — | US | disclosed |
| US-20080318978-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ALDOSTERONE SYNTHASE INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318978-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ALDOSTERONE SYNTHASE INHIBITORS | CYP11B1, CYP11B2, CYP21A2 | CDC7 2721/4885PKN1 377/4885PKN2 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.