SCHEMBL766561

SCHEMBL766561

CCCCCc1ccccc1OP(=O)(Oc1ccccc1CCCCC)Oc1ccccc1CCCCC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
ALOX5 P09917 1/20 0.49
PTGS2 P35354 1/20 0.49
PPARA Q07869 2/20 0.47
LIPG Q9Y5X9 1/20 0.46
PPARG P37231 1/20 0.44
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446002 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL29522962 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL2770599 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL10878267 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL124086 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL2821133 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL11068354 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL9507916 0.98 THRA (0.55) THRATHRBALOX5PTGS2PPARA
SCHEMBL8013169 0.97 THRA (0.54) THRATHRBALOX5PTGS2PPARA
Phosphine SCHEMBL6813551 0.95 THRA (0.52) THRATHRBALOX5PTGS2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436654-A ORGANIC PHOSPHATE OR PHOSPHONATE AND TRICARBOXYLIC ESTER HITACHI, LTD. (JP) 1984-03-13 US claimed
EP-2177595-B2 Lubricating composition with good oxidative stability and reduced deposit formation AFTON CHEMICAL CORP (US) 2024-05-15 EP disclosed
US-10865357-B2 Lubricating oil composition with improved oxidation retention and reduced sludge and varnish formation PHILLIPS 66 COMPANY (US) 2020-12-15 US disclosed
US-10435609-B2 Hydrophilic ether carboxylic acids as lubricant for salt based drilling systems EMERY OLEOCHEMICALS GMBH (DE) 2019-10-08 US disclosed
EP-3242919-B1 HYDROPHILIC ETHER CARBOXYLIC ACIDS AS LUBRICANT FOR SALT BASED DRILLING SYSTEMS EMERY OLEOCHEMICALS GMBH (DE) 2019-03-13 EP disclosed
US-10227545-B2 Additives for oilfield and industrial applications EMERY OLEOCHEMICALS GMBH (DE) 2019-03-12 US disclosed
EP-3242920-B1 NEW ADDITIVES FOR OILFIELD AND INDUSTRIAL APPLICATIONS EMERY OLEOCHEMICALS GMBH (DE) 2018-12-19 EP disclosed
WO-2018136735-A1 LUBRICATING OIL COMPOSITION WITH IMPROVED OXIDATION RETENTION AND REDUCED SLUDGE AND VARNISH FORMATION PHILLIPS 66 COMPANY (US) 2018-07-26 WO disclosed
US-20180208867-A1 LUBRICATING OIL COMPOSITION WITH IMPROVED OXIDATION RETENTION AND REDUCED SLUDGE AND VARNISH FORMATION PHILLIPS 66 COMPANY (US) 2018-07-26 US disclosed
US-20170342341-A1 NEW ADDITIVES FOR OILFIELD AND INDUSTRIAL APPLICATIONS BANK OF AMERICA, N.A., AS THE ADMINISTRATIVE AGENT 2017-11-30 US disclosed
WO-2005003265-A1 GEL ADDITIVES FOR FUEL THAT REDUCE SOOT AND/OR EMISSIONS FROM ENGINES THE LUBRIZOL CORPORATION (US) 2005-01-13 WO disclosed
US-20040266630-A1 Novel additive composition that reduces soot and/or emissions from engines THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-30 US disclosed
US-20040266631-A1 Gels that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION 2004-12-30 US disclosed
US-20040261313-A1 Gel additives for fuel that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-30 US disclosed
WO-2004007653-A9 SLOW RELEASE LUBRICANT ADDITIVES GEL LUBRIZOL CORP (US) 2004-06-10 WO disclosed
WO-2004007653-A2 SLOW RELEASE LUBRICANT ADDITIVES GEL THE LUBRIZOL CORPORATION (US) 2004-01-22 WO disclosed
US-20040014614-A1 Slow release lubricant additives gel LUBRIZOL CORPORATION, THE 2004-01-22 US disclosed
EP-0291521-A1 SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS. LUBRIZOL CORP (US) 1988-11-23 EP disclosed
WO-1988003552-A2 SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1988-05-19 WO disclosed
US-4436654-A ORGANIC PHOSPHATE OR PHOSPHONATE AND TRICARBOXYLIC ESTER HITACHI, LTD. (JP) 1984-03-13 US disclosed