Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10911152 | 0.99 | NOD2 (0.54) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL4452390 | 0.94 | NOD2 (0.55) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL3229330 | 0.93 | NOD2 (0.57) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL342953 | 0.93 | NOD2 (0.57) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL5270133 | 0.93 | NOD2 (0.57) | NOD2MAPK1ALDH1A1THRBESR1 | |
| Water SCHEMBL769017 | 0.93 | NOD2 (0.57) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL8750743 | 0.92 | NOD2 (0.46) | NOD2MAPK1ALDH1A1THRBESR1 | |
| Alanine SCHEMBL11120060 | 0.92 | NOD2 (0.56) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL4450131 | 0.91 | NOD2 (0.55) | NOD2MAPK1ALDH1A1THRBESR1 | |
| SCHEMBL11289575 | 0.91 | NOD2 (0.55) | NOD2MAPK1ALDH1A1THRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884084-B2 | Bone loss preventing and bone regeneration or bone formation promoting pharmaceutical composition comprising muramyl dipeptide | SNU R&DB FOUNDATION (KR) | 2018-02-06 | — | — | US | claimed |
| US-20150141352-A1 | BONE LOSS PREVENTING AND BONE REGENERATION OR BONE FORMATION PROMOTING PHARMACEUTICAL COMPOSITION COMPRISING MURAMYL DIPEPTIDE | SNU R&DB FOUNDATION (KR) | 2015-05-21 | — | — | US | claimed |
| EP-0513861-B1 | Vaccine adjuvant comprising a tetra-polyol | SYNTEX INC (US) | 1997-02-26 | — | — | EP | claimed |
| US-5376369-A | Improved immunological response | SYNTEX (U.S.A.) INC. (US) | 1994-12-27 | — | — | US | claimed |
| EP-0315153-B1 | Vaccine adjuvant | SYNTEX INC (US) | 1994-05-11 | — | — | EP | claimed |
| EP-0513861-A1 | Vaccine adjuvant comprising a tetra-polyol | SYNTEX (U.S.A.) INC. (US) | 1992-11-19 | — | — | EP | claimed |
| US-4933179-A | IMMUNOLOGY | SYNTEX (U.S.A.) INC. (US) | 1990-06-12 | — | — | US | claimed |
| US-4857318-A | Bordetella bronchiseptica pilus subunit protein vaccine effective against bordetella pertussis | SYNTEX (U.S.A.) INC. (US) | 1989-08-15 | — | — | US | claimed |
| EP-0315153-A2 | Vaccine adjuvant | SYNTEX (U.S.A.) INC. (US) | 1989-05-10 | — | — | EP | claimed |
| US-4684625-A | Method for enhancing the anti-infective activity of muramyldipeptide derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-08-04 | — | — | US | claimed |
| US-4522811-A | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides | SYNTEX (U.S.A.) INC. (US) | 1985-06-11 | — | — | US | claimed |
| US-9884084-B2 | Bone loss preventing and bone regeneration or bone formation promoting pharmaceutical composition comprising muramyl dipeptide | SNU R&DB FOUNDATION (KR) | 2018-02-06 | — | — | US | disclosed |
| US-20150141352-A1 | BONE LOSS PREVENTING AND BONE REGENERATION OR BONE FORMATION PROMOTING PHARMACEUTICAL COMPOSITION COMPRISING MURAMYL DIPEPTIDE | SNU R&DB FOUNDATION (KR) | 2015-05-21 | — | — | US | disclosed |
| US-20090191226-A2 | ADJUVANT FORMULATION COMPRISING A SUBMICRON OIL DROPLET EMULSION | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| US-20040057958-A1 | Immunogenicity-enhancing carriers and compositions thereof and methods of using the same | CELL THERAPEUTICS, INC. | 2004-03-25 | — | — | US | disclosed |
| US-4606918-A | IMMUNOSTIMULATING GLYCOPEPTIDE; EMULSIFICATION | SYNTEX (U.S.A.) INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4522811-A | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides | SYNTEX (U.S.A.) INC. (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0026746-B1 | COMBINATORY COMPOSITIONS FOR USE IN A METHOD FOR ENHANCING THE ACTIVITY OF ANTIBIOTICS, ANTIBIOTIC PREPARATIONS HAVING ENHANCED ACTIVITY AND PROCESS FOR THEIR PRODUCTION | CIBA-GEIGY AG (CH) | 1985-04-10 | — | — | EP | disclosed |
| EP-0135376-A2 | Polyoxypropylene-polyoxyethylene block polymer based adjuvants and vaccines using them | SYNTEX (U.S.A.) INC. (US) | 1985-03-27 | — | — | EP | disclosed |
| EP-0026746-A1 | Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production | CIBA-GEIGY AG (CH) | 1981-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141352-A1 | BONE LOSS PREVENTING AND BONE REGENERATION OR BONE FORMATION PROMOTING PHARMACEUTICAL COMPOSITION COMPRISING MURAMYL DIPEPTIDE | MYADM, DPP9, DPP3 | NOD2 250/4885MAPK1 2538/4885ALDH1A1 4159/4885 |
| US-20090191226-A2 | ADJUVANT FORMULATION COMPRISING A SUBMICRON OIL DROPLET EMULSION | MYD88, CD14, IAPP | NOD2 38/4885MAPK1 2705/4885ALDH1A1 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.