SCHEMBL4446211

SCHEMBL4446211

CCc1cccc(OP(C)(=O)O)c1CC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
INPPL1 O15357 1/20 0.39
INPP5B P32019 1/20 0.39
INPP5A Q14642 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SRC P12931 1/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
HTR1A P08908 2/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL761162 0.88 INPPL1 (0.53) GABRA1GABRB2INPPL1INPP5BINPP5A
SCHEMBL2150379 0.88 GABRA1 (0.41) CYP2C19SMN1; SMN2GABRA1GABRB2INPPL1
SCHEMBL4446208 0.87 GABRA1 (0.39) CYP2C19SMN1; SMN2GABRA1GABRB2INPPL1
SCHEMBL4454429 0.85 GABRA1 (0.38) CYP2C19SMN1; SMN2GABRA1GABRB2INPPL1
SCHEMBL778837 0.84 SMN1; SMN2 (0.49) CYP2C19SMN1; SMN2GABRA1GABRB2INPPL1
SCHEMBL761161 0.84 GABRA1 (0.39) GABRA1GABRB2INPPL1INPP5BINPP5A
SCHEMBL6832959 0.83 GABRA1 (0.39) GABRA1GABRB2INPPL1INPP5BINPP5A
SCHEMBL4462593 0.82 CETP (0.37) GABRA1GABRB2INPPL1INPP5BINPP5A
SCHEMBL4454048 0.82 SRC (0.37) CYP2C19SMN1; SMN2GABRA1GABRB2INPPL1
SCHEMBL4460758 0.82 LTB4R (0.42) CYP2C19SMN1; SMN2INPPL1INPP5BINPP5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed