Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | FABP7 | O15540 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623157 | 0.91 | KMT2A (0.55) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL14759878 | 0.89 | KMT2A (0.60) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL5497604 | 0.87 | KMT2A (0.55) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL31562943 | 0.86 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL9514726 | 0.86 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL16476528 | 0.86 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL10071038 | 0.85 | KMT2A (0.50) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL1853371 | 0.85 | KMT2A (0.64) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL31562946 | 0.85 | KMT2A (0.50) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL31562944 | 0.85 | KMT2A (0.50) | KMT2AFABP5FABP7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2104682-A2 | DIAGNOSIS AND TREATMENT OF ALZHEIMER'S AND OTHER NEURODEMENTING DISEASES | Philipps-Universität Marburg (DE) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008084402-A2 | DIAGNOSIS AND TREATMENT OF ALZHEIMER'S AND OTHER NEURODEMENTING DISEASES | PHILIPPS-UNIVERSITAET MARBURG (US) | 2008-07-17 | — | — | WO | disclosed |