Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.48 |
| ▸ | FABP7 | O15540 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31562943 | 1.00 | KMT2A (0.51) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL3623157 | 0.92 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL14759878 | 0.90 | KMT2A (0.60) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL5497604 | 0.89 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL16476528 | 0.88 | KMT2A (0.51) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL4446336 | 0.86 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL1853371 | 0.86 | KMT2A (0.64) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL31562946 | 0.86 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL10071038 | 0.86 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL31562944 | 0.86 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320967-B1 | ANF derivatives with novel bridging | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1993-12-08 | — | — | EP | disclosed |
| US-5242974-A | Polymer formation on substrate with tether molecule, unmasking of protective group to form cyclic polymer, bond clevage | AFFYMAX TECHNOLOGIES N.V. (NL) | 1993-09-07 | — | — | US | disclosed |
| US-4891358-A | ATRIAL NATRIURETIC FACTOR | BIO-MEGA INC. (CA) | 1990-01-02 | — | — | US | disclosed |
| EP-0320967-A2 | ANF derivatives with novel bridging | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1989-06-21 | — | — | EP | disclosed |