SCHEMBL4446563

SCHEMBL4446563

Oc1c(Cl)ccc(-c2ccnnn2)c1Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALPL P05186 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979200 0.75 CNR2 (0.46)
SCHEMBL6233046 0.73 CYP19A1 (0.36)
SCHEMBL2117777 0.71 MAPT (0.45) ALPL
SCHEMBL28301379 0.71 IDO1 (0.44) ALPL
SCHEMBL6677481 0.69 TYR (0.43)
SCHEMBL4455573 0.69
SCHEMBL1534219 0.68 HPGD (0.39)
SCHEMBL28305414 0.68 PTPN22 (0.44)
SCHEMBL379708 0.67 KDM4E (0.32)
SCHEMBL45025 0.67 IDO1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009131958-A2 COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING TRIAZINE DERIVATIVES INSTITUTE FOR ONEWORLD HEALTH (US) 2009-10-29 WO claimed
WO-2009131958-A2 COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING TRIAZINE DERIVATIVES INSTITUTE FOR ONEWORLD HEALTH (US) 2009-10-29 WO disclosed