SCHEMBL6677481

SCHEMBL6677481

Oc1ccc(-c2ccnnn2)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.43
MAPT P10636 4/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 2/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
RUNX1 Q01196 1/20 0.41
CBFB Q13951 1/20 0.41
ALOX5 P09917 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 2/20 0.38
KMT2A Q03164 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
AMY1A P0DUB6 1/20 0.37
ESR1 P03372 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28164879 0.81 TRPA1 (0.42) MAPTALDH1A1GAAHPGDNPC1
SCHEMBL45025 0.78 IDO1 (0.43) MAPTALDH1A1HPGDRAB9AMEN1
SCHEMBL29501476 0.78 IDO1 (0.43) MAPTALDH1A1HPGDRAB9AMEN1
SCHEMBL29189675 0.77 LTA4H (0.44) MAPTHTTNPC1RAB9AMEN1
SCHEMBL28454726 0.77 IDO1 (0.42) MAPTALDH1A1HPGDRAB9AMEN1
SCHEMBL9685095 0.77 ALOX5 (0.44) TYRMAPTALDH1A1GAAHPGD
Hydrochloric Acid SCHEMBL21412263 0.77 IDO1 (0.42) MAPTALDH1A1HPGDRAB9AMEN1
SCHEMBL6233046 0.77 CYP19A1 (0.36) AMY1A
SCHEMBL28916520 0.74 LTA4H (0.36) MAPTALDH1A1GAAHTTNPC1
SCHEMBL21411653 0.74 KCNH2 (0.52) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3161089-A1 PRESSURE SENSITIVE ADHESIVE COMPOSITION INCLUDING ULTRAVIOLET LIGHT-ABSORBING OLIGOMER 3M Innovative Properties Company (US) 2017-05-03 EP disclosed
WO-2015200669-A1 PRESSURE SENSITIVE ADHESIVE COMPOSITION INCLUDING ULTRAVIOLET LIGHT-ABSORBING OLIGOMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-30 WO disclosed
CN-1184212-C Process for making 2-(2-hydroxy-4-alkoxyphenyl)-4,6-bisaryl-1,3,5-triazines CTYEC TECHNOLOGY CORP (US) 2005-01-12 CN disclosed
EP-1109791-B1 PROCESS FOR MAKING 2-(2-HYDROXY-4-ALKOXYPHENYL)-4,6-BISARYL-1,3,5-TRIAZINES CYTEC TECH CORP (US) 2004-11-03 EP disclosed
EP-0500496-B2 Stabilised polymers containing heteroatoms in the main chain CIBA SC HOLDING AG (CH) 2002-01-30 EP disclosed
CN-1317000-A Process for the production of 2- (2-hydroxy-4-alkoxyphenyl) -4, 6-bisaryl-1, 3, 5-triazines CYTEC TECH CORP (US) 2001-10-10 CN disclosed
US-6297378-B1 CATALYZED REACTION OF ARYL ETHERS AND HALOGENATED TRIAZINE COMPOUNDS. CYTEC TECHNOLOGY CORP. 2001-10-02 US disclosed
WO-2000014076-A1 PROCESS FOR MAKING 2,4-DIHYDROXYPHENYL AND 2-HYDROXY-4-ALKOXYPHENYL SUBSTITUTED TRIAZINE COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-16 WO disclosed
EP-0500496-B1 Stabilised polymers containing heteroatoms in the main chain CIBA GEIGY AG (CH) 1997-08-27 EP disclosed
US-5412008-A Hydroxyphenyl triazines CIBA-GEIGY CORPORATION (US) 1995-05-02 US disclosed
EP-0506615-B1 Stabilized methylmethacrylate polymers CIBA GEIGY AG (CH) 1995-02-22 EP disclosed
US-5288778-A Containing hydroxyphenyltriazine CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed
EP-0500496-A1 Stabilised polymers containing heteroatoms in the main chain CIBA-GEIGY AG (CH) 1992-08-26 EP disclosed