Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6379454 | 0.98 | ALOX5 (0.42) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL11534783 | 0.85 | ALOX5 (0.44) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL6021351 | 0.81 | TSHR (0.41) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL13447237 | 0.81 | ALOX5 (0.44) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL6021627 | 0.81 | ALDH1A1 (0.41) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL24162104 | 0.81 | ALOX5 (0.44) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL6021654 | 0.78 | HPGD (0.43) | ALOX5CES2CES1KEAP1TSHR | |
| Hydrochloric Acid SCHEMBL6382476 | 0.77 | HPGD (0.43) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL22815357 | 0.77 | ALOX5 (0.46) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL11666936 | 0.77 | ALOX5 (0.46) | ALOX5CES2CES1KEAP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225627-B1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | UNIV NORTHWEST (CN) | 2021-11-03 | — | — | EP | disclosed |
| EP-3225627-A1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Northwest University (CN) | 2017-10-04 | — | — | EP | disclosed |
| US-20170267718-A1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | NORTHWEST UNIVERSITY (CN) | 2017-09-21 | — | — | US | disclosed |
| EP-2125772-A1 | A PROCESS FOR THE PREPARATION OF DULOXETIN AND NEW KEY INTERMEDIATES FOR USE THEREIN | Richter Gedeon NYRT (HU) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008078124-A1 | A PROCESS FOR THE PREPARATION OF DULOXETIN AND NEW KEY INTERMEDIATES FOR USE THEREIN | RICHTER GEDEON NYRT. (HU) | 2008-07-03 | — | — | WO | disclosed |
| EP-1664014-A2 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF BETA-AMINO KETONES | LONZA AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005021527-A2 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF BETA-AMINO KETONES | LONZA AG (CH) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267718-A1 | TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | VIP, PREP, ACE | ALOX5 1528/4885CES2 3420/4885CES1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.