SCHEMBL4447113

SCHEMBL4447113

Clc1ccc(-c2ccc(Cl)c(Cl)c2)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.65
TP53 P04637 3/20 0.64
SRD5A2 P31213 1/20 0.49
CYP1B1 Q16678 1/20 0.48
HSD11B1 P28845 2/20 0.44
EIF4E P06730 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
DHFR P00374 1/20 0.42
MARS1 P56192 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456490 0.90 AHR (0.69) AHRTP53SRD5A2CYP1B1HSD11B1
SCHEMBL4445026 0.84 AHR (0.67) AHRTP53CYP1B1EIF4ENPC1
SCHEMBL2933108 0.83 AHR (0.67) AHRTP53SRD5A2HSD11B1NPC1
SCHEMBL2463985 0.81 AHR (0.53) AHRTP53SRD5A2HSD11B1ESR1
SCHEMBL2502464 0.81 TSHR (0.56) AHRTP53CYP1B1NPC1RAB9A
Iodide SCHEMBL27785032 0.80
Ammonia Solution, Strong SCHEMBL3217070 0.80
SCHEMBL22730 0.80
SCHEMBL29349499 0.80
SCHEMBL8873179 0.80 TP53 (1.00) AHRTP53SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN claimed
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-106216384-B A kind of method of manganese oxide minerals collaboration manganese dioxide degradation PCBs in Soil 浙江工业大学 2019-05-31 CN claimed
CN-112753133-B Multilayer patch antenna 高通股份有限公司 2024-07-05 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN disclosed
CN-110607279-B 3D culture system of primary tumor cells, and culture method and application thereof 深圳优圣康医学检验实验室 2023-09-19 CN disclosed
CN-219290587-U Modular controller 百欧韦弗有限公司 2023-07-04 CN disclosed
CN-116234161-A Circuit board and computing device 超聚变数字技术有限公司 2023-06-06 CN disclosed
CN-218630558-U Modular controller 百欧韦弗有限公司 2023-03-14 CN disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
CN-1775332-A Method for reinforcing diphenyl polychlorisde biodegradation utilizing sucrose fat UNIV DALIAN TECH (CN) 2006-05-24 CN disclosed
EP-1616022-A2 TEST SYSTEM FOR DETECTING CONTAMINANTS Crown Vision Systems Limited (GB) 2006-01-18 EP disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
WO-2004090156-A2 TEST SYSTEM FOR DETECTING CONTAMINANTS CROWN VISION SYSTEMS LIMITED (GB) 2004-10-21 WO disclosed
US-4902730-A Fibre reinforced polyphenylene sulphide BAYER AKTIENGESELLSCHAFT (DE) 1990-02-20 US disclosed
US-4786712-A FROM AROMATIC DIHALOGEN COMPOUND AND SODIUM SULFIDE BAYER AKTIENGESELLSCHAFT (DE) 1988-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 AHR 3353/4885TP53 2372/4885SRD5A2 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.