Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501282 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL28474884 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL28346982 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL18722590 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL13451749 | 0.97 | DNM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL23951461 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL2854096 | 0.97 | DNM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL2892345 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL30232622 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL31596116 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399318-A1 | RENEWABLE OILS: COMPOSITION, PROCESS OF MAKING AND FORMULATION | RiKarbon, Inc (US) | 2023-12-14 | — | — | US | disclosed |
| EP-3116722-B1 | METHOD AND APPARATUS FOR PRODUCING A CUSTOM SIZED CANVAS STRETCHER FRAME | SIEGEL MARVIN (US) | 2020-05-27 | — | — | EP | disclosed |
| CN-110408266-A | Inorganic nano material prints ink and its preparation method and application | TCL CORP | 2019-11-05 | — | — | CN | disclosed |
| EP-1493744-B1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-7553897-B2 | Organic thiol stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY (US) | 2009-06-30 | — | — | US | disclosed |
| US-20090005389-A1 | 2,5 Diaza-Bicyclo [2.2.1] Heptane Derivatives as Calcium Channel Blockers | MERCK SHARP & DOHME CORP. | 2009-01-01 | — | — | US | disclosed |
| EP-1978963-A2 | 2,5 DIAZA-BICYCLOÝ2.2.1¨HEPTANE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Merck & Co., Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084394-A2 | 2,5 DIAZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070161728-A1 | Organic Thiol Stabilizers and Plasticizers for Halogen-Containing Polymers | COLLEGE OF WILLIAM AND MARY (US) | 2007-07-12 | — | — | US | disclosed |
| US-6852867-B2 | Process for preparation of a benzofuran derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-08 | — | — | US | disclosed |
| US-6353105-B1 | INHIBITORS OF 5-HYDROXY-TRYPTAMINE REUPTAKE OF A MONOAMINE TRANSPORTER; ANALOGS OF COCAINE; | ORGANIX, INC. | 2002-03-05 | — | — | US | disclosed |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2002-01-24 | — | — | US | disclosed |
| EP-0812820-B1 | TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM | TAKASAGO PERFUMERY CO LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6172264-B1 | REACTING A TRIPHENYLAMINE WITH A VILSMEIER IN PRESENCE OF ACID CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0996619-A1 | TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT | ORGANIX, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5989765-A | CHARGE TRANSPORT MATERIAL IS A TRIPHENYLAMINE DERIVATIVE WHERE ONE OF THE PHENYL GROUPS OF THE TRIPHENYL AMINE HAS A DIPHENYLBUTADIENYL-SUBSTITUENT AND THE OTHER TWO PHENYL GROUPS HAVE A DIPHENYLBUTADIENYL- OR DIPHENYLVINYL-FRAMEWORK | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5948933-A | THERAPY FOR DRUG ABRUSE | ORGANIX, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| US-5910610-A | Triphenylamine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-06-08 | — | — | US | disclosed |
| WO-1999002526-A1 | TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT | ORGANIX, INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| EP-0812820-A1 | TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM | Takasago International Corporation (JP) | 1997-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005389-A1 | 2,5 Diaza-Bicyclo [2.2.1] Heptane Derivatives as Calcium Channel Blockers | TRPV1, CACNA1D, CACNA1S | OPRM1 722/4885TSHR 3059/4885THRB 1576/4885 |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | SLC6A2, SLC6A4, SLC6A3 | OPRM1 110/4885TSHR 510/4885THRB 436/4885 |
| US-20230399318-A1 | RENEWABLE OILS: COMPOSITION, PROCESS OF MAKING AND FORMULATION | CBR1, CBR3, AKR1C3 | OPRM1 2515/4885TSHR 1547/4885THRB 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.