Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456816 | 0.89 | HPGD (0.47) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL4457921 | 0.82 | HPGD (0.60) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL1703922 | 0.81 | HPGD (0.53) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL1703594 | 0.81 | HPGD (0.53) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL1703635 | 0.81 | HPGD (0.53) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL13045356 | 0.81 | HPGD (0.53) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL19739574 | 0.77 | HPGD (0.56) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL13300379 | 0.76 | NAMPT (0.47) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL13300165 | 0.76 | NAMPT (0.47) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL29263737 | 0.75 | HPGD (0.59) | HPGDMAPK1ALDH1A1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |