Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19739574 | 0.95 | HPGD (0.56) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL4447716 | 0.82 | HPGD (0.49) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL4456816 | 0.81 | HPGD (0.47) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL28431281 | 0.76 | HPGD (0.61) | HPGDMAPK1ALDH1A1 | |
| SCHEMBL221237 | 0.75 | ACHE (0.42) | HPGDMAPK1ALDH1A1DRD2ACHE | |
| SCHEMBL29263737 | 0.74 | HPGD (0.59) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL28431289 | 0.74 | HPGD (0.60) | HPGDMAPK1ALDH1A1 | |
| SCHEMBL222333 | 0.73 | MAOB (0.52) | ALDH1A1HTR1AHTR7DRD2ACHE | |
| SCHEMBL4447186 | 0.73 | HPGD (0.58) | HPGDMAPK1ALDH1A1HTR1AHTR7 | |
| SCHEMBL28747330 | 0.73 | HDAC8 (0.53) | HPGDMAPK1ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |