Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616013 | 0.80 | THRB (0.33) | THRB | |
| SCHEMBL8466921 | 0.77 | TSHR (0.37) | THRBALDH1A1TSHR | |
| SCHEMBL9546011 | 0.67 | TSHR (0.37) | THRBALDH1A1TSHR | |
| SCHEMBL3266194 | 0.66 | — | — | |
| SCHEMBL20624825 | 0.65 | THRB (0.39) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL27910295 | 0.65 | TSHR (0.55) | THRBALDH1A1TSHR | |
| SCHEMBL303731 | 0.65 | CES2 (0.45) | THRBTSHRHSD17B10 | |
| SCHEMBL1991763 | 0.63 | THRB (0.70) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL2742411 | 0.63 | THRB (0.70) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL252654 | 0.63 | TSHR (0.62) | THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | claimed |
| EP-2077292-B1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORP (TW) | 2013-08-14 | — | — | EP | claimed |
| EP-2077292-A1 | Polysiloxane-based prepolymer and hydrogel | Far Eastern Texile Ltd. (CN) | 2009-07-08 | — | — | EP | claimed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | disclosed |
| US-20210011200-A1 | FUNCTIONAL CONTACT LENS AND METHOD FOR DYEING THE SAME | VIZIONFOCUS INC. (TW) | 2021-01-14 | — | — | US | disclosed |
| CN-102115515-B | Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom | FAR EASTERN NEW CENTURY CORP | 2014-06-18 | — | — | CN | disclosed |
| EP-2077292-B1 | Polysiloxane-based prepolymer and hydrogel | FAR EASTERN NEW CENTURY CORP (TW) | 2013-08-14 | — | — | EP | disclosed |
| CN-101469068-B | Prepolymer containing silicon and silicon-containing glue and contact lens prepared therefrom | FAR EASTERN APPAREL CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-102115515-A | Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom | FAR EASTERN NEW CENTURY CORP | 2011-07-06 | — | — | CN | disclosed |
| EP-2077292-A1 | Polysiloxane-based prepolymer and hydrogel | Far Eastern Texile Ltd. (CN) | 2009-07-08 | — | — | EP | disclosed |
| EP-1789821-A2 | SILICONE HYDROGEL CONTACT LENSES | ASAHIKASEI AIME CO., Ltd. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006026474-A2 | SILICONE HYDROGEL CONTACT LENSES | ASAHIKASEI AIME CO. LTD. (JP) | 2006-03-09 | — | — | WO | disclosed |