SCHEMBL4448076

SCHEMBL4448076

[c]1ccc(Sc2ccccc2)cc1Sc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.40
MAOB P27338 3/20 0.40
HTR2C P28335 2/20 0.39
HTR6 P50406 1/20 0.39
MCL1 Q07820 2/20 0.36
BCL2 P10415 1/20 0.36
HPGD P15428 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PLA2G1B P04054 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
SLC6A4 P31645 1/20 0.32
SIRT1 Q96EB6 1/20 0.31
PDE7A Q13946 1/20 0.31
KDR P35968 1/20 0.30
MAPK1 P28482 1/20 0.30
ANXA2 P07355 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28003164 0.80 PDE7A (0.39) HPGDALDH1A1MAPTSMN1; SMN2MGLL
SCHEMBL921075 0.78 MAOA (0.39) MAOAMAOBHTR2CHTR6MCL1
SCHEMBL28437477 0.78 MAOA (0.39) MAOAMAOBHTR2CHTR6MCL1
SCHEMBL9003412 0.78 MAOA (0.39) MAOAMAOBHTR2CHTR6MCL1
SCHEMBL28003218 0.76 ALDH1A1 (0.39) MAOAMAOBHPGDALDH1A1MAPT
SCHEMBL15018242 0.76 MAOA (0.52) MAOAMAOBMCL1HPGDALDH1A1
SCHEMBL28002872 0.76 TSHR (0.39) PDE7A
SCHEMBL4449796 0.76 MAOA (0.40) MAOAMAOBHTR2CHTR6MCL1
SCHEMBL237661 0.76 HPGD (0.38) MAOAMAOBHTR2CHTR6MCL1
SCHEMBL8573238 0.73 MAOA (0.36) MAOAMAOBHTR2CHTR6MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7550639-B2 Process for producing olefin oligomer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-23 US disclosed
US-7323611-B2 Process for producing olefin oligomer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2008-01-29 US disclosed
US-20070027350-A1 PROCESS FOR PRODUCING OLEFIN OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-01 US disclosed
US-20060293546-A1 PROCESS FOR PRODUCING OLEFIN OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-12-28 US disclosed