SCHEMBL4448287

SCHEMBL4448287

[CH2]COC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
RECQL P46063 1/20 0.50
SERPINE1 P05121 2/20 0.47
ALOX5 P09917 2/20 0.44
PTGS1 P23219 2/20 0.44
PTGS2 P35354 2/20 0.44
CA2 P00918 4/20 0.44
CA1 P00915 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
ALDH1A1 P00352 3/20 0.42
POLB P06746 1/20 0.42
TYR P14679 1/20 0.42
GAA P10253 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
GLRA3 O75311 1/20 0.42
GLRB P48167 1/20 0.42
TNFRSF1A P19438 1/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6918210 0.84 CA2 (0.59) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL10705024 0.83 SERPINE1 (0.56) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL7594781 0.82 LMNA (0.46) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL10986042 0.81 SERPINE1 (0.62) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL10726674 0.81 LMNA (0.49) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL10787434 0.81 ESR1 (0.53) LMNARECQLSERPINE1CA2CA1
SCHEMBL10726669 0.81 LMNA (0.49) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL7943043 0.81 LMNA (0.49) LMNARECQLSERPINE1ALOX5PTGS1
SCHEMBL9246950 0.81 ESR1 (0.58) LMNARECQLSERPINE1
Methylamine SCHEMBL8647392 0.81 CA2 (0.56) LMNARECQLSERPINE1ALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3992434-A Ethanol- and substituted ethanolamides of hindered 3,5-dialkyl-4-hydroxybenzoic acids AMERICAN CYANAMID COMPANY (US) 1976-11-16 US claimed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-20090306361-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2009-12-10 US disclosed
US-20060233973-A1 Cellulose ester film, manufacturing method thereof, optical film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2006-10-19 US disclosed
US-5025048-A Oxygen resistant, storage-stable curable polysiloxanes hydrosilated by a polycyclic polyene and a compound containing an amine and a hydroxy, both sterically hindered HERCULES INCORPORATED (US) 1991-06-18 US disclosed
US-4226999-A ANTIOXIDANTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1980-10-07 US disclosed
US-4202816-A ENOL-PIPERIDINE METAL COMPLEXES CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed
US-4198334-A HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS CIBA-GEIGY CORPORATION (US) 1980-04-15 US disclosed
US-4148784-A HEAT, LIGHT AND OXIDATION RESISTANCE FOR SYNTHETIC POLYMERS CIBA-GEIGY CORPORATION (US) 1979-04-10 US disclosed
US-4145556-A N,N*-BIS(ALKYLHYDROXYPHENYL)ALKANOYLOXY-HYDROCARBYL)OXAMIDES MONSANTO COMPANY (US) 1979-03-20 US disclosed