Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 4/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12444452 | 0.91 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC6PTGER4 | |
| SCHEMBL12515762 | 0.91 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC6PTGER4 | |
| SCHEMBL15746733 | 0.82 | ALDH1A1 (0.38) | HDAC3HDAC1HDAC2HDAC6PTGER4 | |
| SCHEMBL15746653 | 0.77 | KMT2A (0.40) | MAOBMAPK1 | |
| SCHEMBL2216339 | 0.75 | HDAC6 (0.44) | HDAC3HDAC1HDAC2HDAC6MAOB | |
| SCHEMBL12935668 | 0.74 | KMT2A (0.42) | MAOBMAPK1 | |
| SCHEMBL1503297 | 0.72 | MAPT (0.43) | MAPK1 | |
| SCHEMBL1503145 | 0.71 | MAOB (0.37) | MAOBMAPK1 | |
| SCHEMBL4316603 | 0.69 | PTPN1 (0.38) | MAPK1 | |
| SCHEMBL2146752 | 0.68 | HSD11B1 (0.35) | MAOBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | claimed |