SCHEMBL4448527

SCHEMBL4448527

CO[Si](CC[CH]CC#N)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28079114 0.77 LMNA (0.33)
SCHEMBL28044097 0.70 LMNA (0.36)
SCHEMBL235898 0.69 ALDH1A1 (0.37) TSHR
Water SCHEMBL718559 0.67
SCHEMBL28079118 0.67 LMNA (0.42) TSHR
SCHEMBL491152 0.66
SCHEMBL1039273 0.66 LMNA (0.31)
SCHEMBL16263514 0.65
SCHEMBL126260 0.65 TSHR (0.42) TSHR
SCHEMBL19066288 0.64 LMNA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2132235-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS Commonwealth Scientific and Industrial Research Organisation (AU) 2009-12-16 EP claimed
WO-2008103144-A1 PROCESS FOR TRANSFORMING THE END GROUPS OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-08-28 WO claimed