Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769748 | 0.84 | ESR1 (0.54) | TDP1HPGDLMNAMAPK1CYP3A4 | |
| SCHEMBL186928 | 0.81 | APP (0.51) | APPBLMTDP1KDM4EHPGD | |
| SCHEMBL186927 | 0.81 | APP (0.51) | APPBLMTDP1KDM4EHPGD | |
| SCHEMBL15540843 | 0.80 | SMN1; SMN2 (0.43) | TDP1HPGDLMNAMAPK1CYP3A4 | |
| SCHEMBL21378827 | 0.78 | TDP1 (0.58) | BLMMAPTRECQLTDP1KDM4E | |
| SCHEMBL32670840 | 0.78 | TDP1 (0.58) | BLMMAPTRECQLTDP1KDM4E | |
| SCHEMBL10567492 | 0.76 | LMNA (0.50) | TDP1LMNAMAPK1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28848203 | 0.76 | TDP1 (0.55) | BLMMAPTRECQLTDP1KDM4E | |
| SCHEMBL2409788 | 0.75 | CA12 (0.44) | APPHSD17B10 | |
| SCHEMBL8803384 | 0.75 | TSHR (0.39) | MAPTTDP1HPGDLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125195-A2 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | Polyintell (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008132384-A2 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | POLYINTELL (FR) | 2008-11-06 | — | — | WO | disclosed |