Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460565 | 0.83 | PTGDR2 (0.75) | PTGDR2HPGDALDH1A1TSHRPOLB | |
| SCHEMBL14290417 | 0.82 | PTGDR2 (0.64) | PTGDR2HPGDALDH1A1TSHRPOLB | |
| SCHEMBL4442738 | 0.81 | KDM4E (0.56) | ALDH1A1TRPA1MTNR1AERN1TP53 | |
| SCHEMBL2219521 | 0.80 | HPGD (0.66) | PTGDR2HPGDALDH1A1TSHRPOLB | |
| SCHEMBL2599760 | 0.80 | ALDH1A1 (0.49) | HPGDALDH1A1TRPA1MTNR1ATSHR | |
| SCHEMBL155442 | 0.79 | HPGD (0.64) | PTGDR2HPGDALDH1A1TSHRPOLB | |
| SCHEMBL2879909 | 0.78 | PTGDR2 (1.00) | PTGDR2ALDH1A1TSHRPOLBCTDSP1 | |
| SCHEMBL671015 | 0.78 | KMT2A (0.54) | HPGDALDH1A1TSHRPOLBTDP1 | |
| SCHEMBL29952214 | 0.78 | PTGDR2 (1.00) | PTGDR2ALDH1A1TSHRPOLBCTDSP1 | |
| SCHEMBL4478065 | 0.78 | PTGDR2 (0.67) | PTGDR2HPGDALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655344-B1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USE | UNIV CATHOLIQUE LOUVAIN (BE) | 2015-11-25 | — | — | EP | disclosed |
| US-9181265-B2 | Substituted 2,3-dihydro-1H-benzo[a]pyrano[2,3-c]phenazines as anti-angiogenic and anti-cancer agents | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2015-11-10 | — | — | US | disclosed |
| US-9181265-B2 | Substituted 2,3-dihydro-1H-benzo[a]pyrano[2,3-c]phenazines as anti-angiogenic and anti-cancer agents | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20130289030-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289030-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012085222-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USE | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2012-06-28 | — | — | WO | disclosed |
| EP-2125825-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2009-12-02 | — | — | EP | disclosed |
| US-20080293757-A1 | ABCA1 ELEVATING COMPOUNDS | ABELMAN MATTHEW | 2008-11-27 | — | — | US | disclosed |
| US-7432276-B2 | ABCA1 elevating compounds | CV THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7423045-B2 | ABCA1 elevating compounds | CV THERAPEUTICS, INC. (US) | 2008-09-09 | — | — | US | disclosed |
| WO-2008079139-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-1907395-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20070191379-A1 | ABCA1 elevating compounds | CV THERAPEUTICS, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070010544-A1 | ABCA1 elevating compounds | CV THERAPEUTICS, INC. | 2007-01-11 | — | — | US | disclosed |
| WO-2007002867-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191379-A1 | ABCA1 elevating compounds | ABCD3, ABCB4, CETP | PTGDR2 2295/4885HPGD 1269/4885ALDH1A1 1804/4885 |
| US-20080293757-A1 | ABCA1 ELEVATING COMPOUNDS | ABCD3, ABCB4, CETP | PTGDR2 2295/4885HPGD 1269/4885ALDH1A1 1804/4885 |
| US-20070010544-A1 | ABCA1 elevating compounds | ABCD3, ABCB4, CETP | PTGDR2 2295/4885HPGD 1269/4885ALDH1A1 1804/4885 |
| US-20130289030-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES | VEGFA, KDR, FLT4 | PTGDR2 62/4885HPGD 550/4885ALDH1A1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.