Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56129 | 0.90 | — | — | |
| SCHEMBL4452105 | 0.86 | LMNA (0.40) | LMNAACE2TSHROPRM1 | |
| SCHEMBL28053963 | 0.83 | LMNA (0.36) | LMNA | |
| SCHEMBL78983 | 0.82 | — | — | |
| SCHEMBL17956344 | 0.80 | OPRM1 (0.46) | LMNAACE2DNM1TSHROPRM1 | |
| SCHEMBL5683936 | 0.80 | OPRM1 (0.46) | LMNAACE2DNM1TSHROPRM1 | |
| SCHEMBL10741611 | 0.80 | OPRM1 (0.46) | LMNAACE2DNM1TSHROPRM1 | |
| SCHEMBL10987570 | 0.80 | OPRM1 (0.46) | LMNAACE2DNM1TSHROPRM1 | |
| SCHEMBL20640390 | 0.80 | OPRM1 (0.46) | LMNAACE2DNM1TSHROPRM1 | |
| SCHEMBL5683987 | 0.80 | OPRM1 (0.46) | LMNAACE2DNM1TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149584-A1 | USE OF HEXAHYDROPHTHALIMIDE COMBINATIONS AS SOFTENER | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-11 | — | — | US | disclosed |