Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9934078 | 0.85 | NR3C2 (0.51) | NR3C2 | |
| SCHEMBL4309482 | 0.83 | L3MBTL1 (0.50) | NR3C2 | |
| Hydrochloric Acid SCHEMBL17161867 | 0.82 | L3MBTL1 (0.49) | NR3C2 | |
| SCHEMBL4309467 | 0.81 | GCK (0.52) | NR3C2 | |
| SCHEMBL20305452 | 0.81 | JAK2 (0.51) | NR3C2 | |
| SCHEMBL24942338 | 0.80 | ACVRL1 (0.57) | — | |
| SCHEMBL4587020 | 0.80 | TDP1 (0.50) | NR3C2 | |
| SCHEMBL6127425 | 0.80 | NR3C2 (1.00) | NR3C2 | |
| SCHEMBL4305979 | 0.78 | JAK2 (0.55) | NR3C2 | |
| SCHEMBL31032910 | 0.78 | JAK2 (0.55) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023753-A1 | 1,3-Thiazole-5-Carboxamides Useful as Cancer Chemotherapeutic Agents | BAYER HEALTHCARE AG (DE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023753-A1 | 1,3-Thiazole-5-Carboxamides Useful as Cancer Chemotherapeutic Agents | MCL1, HDAC5, HDAC6 | NR3C2 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.