SCHEMBL4449040

SCHEMBL4449040

Cc1ccc(NC(=O)c2cc(C(=O)Nc3ccc(C)cc3C)cc(C(=O)Nc3ccc(C)cc3C)c2)c(C)c1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 3/20 0.69
TAS1R1 Q7RTX1 3/20 0.69
TAS1R2 Q8TE23 3/20 0.69
KMT2A Q03164 3/20 0.65
MEN1 O00255 2/20 0.65
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
L3MBTL1 Q9Y468 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.59
ALDH1A1 P00352 1/20 0.59
HTT P42858 1/20 0.59
GFER P55789 1/20 0.57
MAPT P10636 2/20 0.56
PKM P14618 1/20 0.56
TP53 P04637 1/20 0.55
THRB P10828 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12388857 0.91 TAS1R3 (0.71) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL13817565 0.88 TAS1R3 (0.68) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL8820818 0.87 MAPT (0.71) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL11955303 0.86 TAS1R3 (0.75) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL94832 0.84 TAS1R3 (0.64) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL10762097 0.84 MAPT (0.68) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL7302035 0.83 NR1H4 (0.67) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL1998789 0.82 MEN1 (0.67) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL11172094 0.82 TAS1R3 (0.65) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL2560030 0.82 TAS1R3 (0.61) TAS1R3TAS1R1TAS1R2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 US disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 US disclosed