Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.62 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388857 | 0.89 | TAS1R3 (0.71) | TAS1R3TAS1R1TAS1R2L3MBTL1NPC1 | |
| SCHEMBL7304022 | 0.88 | HTT (0.67) | NR1H4L3MBTL1NPC1RAB9AKCNK3 | |
| SCHEMBL7294314 | 0.86 | NR1H4 (0.65) | NR1H4L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL7292413 | 0.86 | HSD17B2 (0.58) | NR1H4L3MBTL1NPC1RAB9AKCNK3 | |
| SCHEMBL29661164 | 0.86 | ALDH1A1 (0.71) | NR1H4L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL2344119 | 0.86 | ALDH1A1 (0.71) | NR1H4L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL15149737 | 0.86 | NR1H4 (0.52) | NR1H4TAS1R3TAS1R1TAS1R2L3MBTL1 | |
| SCHEMBL9978812 | 0.85 | NR1H4 (0.63) | NR1H4TAS1R3TAS1R1TAS1R2L3MBTL1 | |
| SCHEMBL7302951 | 0.85 | SERPINE1 (0.71) | NR1H4TAS1R3TAS1R1TAS1R2L3MBTL1 | |
| SCHEMBL7301522 | 0.85 | MAPT (0.71) | NR1H4L3MBTL1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |