Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28077104 | 0.96 | CA2 (0.33) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL4443699 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL27543121 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL1895697 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL27968185 | 0.95 | CA2 (0.39) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL28365605 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL28319901 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL23149451 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL28985930 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL22396378 | 0.91 | CA2 (0.36) | CA2SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836008-B1 | IN-CONTAINER MINERALIZATION | STUDSVIK INC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-7476194-B2 | In-container mineralization | STUDSVIK, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080119684-A1 | In-Container Mineralization | STUDSVIK, INC. | 2008-05-22 | — | — | US | disclosed |
| EP-1836008-A1 | IN-CONTAINER MINERALIZATION | Studsvik, Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006047070-A1 | IN-CONTAINER MINERALIZATION | STUDSVIK, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060009671-A9 | In-container mineralization | MASON JOHN B | 2006-01-12 | — | — | US | disclosed |
| US-20050096495-A1 | In-container mineralization | STUDSVIK, INC. | 2005-05-05 | — | — | US | disclosed |