⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432436 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL28148916 | 0.79 | — | — | |
| SCHEMBL6831441 | 0.79 | — | — | |
| SCHEMBL42873 | 0.76 | — | — | |
| SCHEMBL524531 | 0.76 | — | — | |
| SCHEMBL42294 | 0.76 | — | — | |
| SCHEMBL12559536 | 0.76 | — | — | |
| SCHEMBL840436 | 0.76 | — | — | |
| SCHEMBL37585 | 0.76 | — | — | |
| SCHEMBL1742981 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115252567-A | Febuxostat osmotic pump sustained-release tablet and preparation method thereof | 广西纯正堂制药有限公司 | 2022-11-01 | — | — | CN | claimed |
| US-20240190815-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | SPRINGWORKS THERAPEUTICS, INC. | 2024-06-13 | — | — | US | disclosed |
| US-11884610-B2 | Crystalline solids of mek inhibitor n-((r)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2024011218-A1 | POLYMERIC NANOPARTICLES FOR LONG ACTING DELIVERY OF A PEPTIDE AND METHODS OF MAKING AND USING THEREOF | BROWN UNIVERSITY (US) | 2024-01-11 | — | — | WO | disclosed |
| US-20230143841-A1 | BETA-KETOACYL-ACP SYNTHASE IV VARIANTS | CORBION BIOTECH, INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| US-20230032403-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | SpringWorks Therapeutics Inc. (US) | 2023-02-02 | — | — | US | disclosed |
| EP-4090735-A1 | BETA-KETOACYL-ACP SYNTHASE IV VARIANTS | Corbion Biotech, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
| CN-115252567-A | Febuxostat osmotic pump sustained-release tablet and preparation method thereof | 广西纯正堂制药有限公司 | 2022-11-01 | — | — | CN | disclosed |
| US-11401538-B2 | Structuring fats and methods of producing structuring fats | CORBION BIOTECH, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| US-4607043-A | SENILITY, AMNESIA | WARNER-LAMBERT COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4584313-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |
| EP-0164853-A1 | (substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids, a process for producing the compounds and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4547519-A | Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-carboxylic acid and benzyl esters and amides thereof and their use in reversing amnesia | WARNER-LAMBERT COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0095345-A2 | Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-carboxylic acids and derivatives as cognition activators | WARNER-LAMBERT COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |
| US-4405631-A | Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'pyrrolidine] compounds and their use as antihypertensive agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0002574-B1 | DISPERSIONS IN PARTICULATE FORM, A PROCESS FOR MAKING THE DISPERSIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-03-23 | — | — | EP | disclosed |
| US-4223006-A | ANHYDROUS HYGROSCOPIC SALT OF CLAVULANIC ACID | BEECHAM GROUP LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| EP-0002574-A1 | Dispersions in particulate form, a process for making the dispersions and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-06-27 | — | — | EP | disclosed |