SCHEMBL4449417

SCHEMBL4449417

C=CCOC(C)OC(=O)/C=C/C(=O)OC(C)OCC=C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.41
MAPT P10636 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643553 1.00 HCAR2 (0.41) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL4449424 0.93 HCAR2 (0.53) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL7198717 0.93 HCAR2 (0.53) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL7196478 0.93 HCAR2 (0.53) HCAR2MAPTCACNA1BAPBA1TSHR
SCHEMBL1886950 0.88 TSHR (0.44) MAPTCACNA1BAPBA1TSHRTDP1
SCHEMBL10482082 0.83 TDP1 (0.37) TSHRTDP1
SCHEMBL10482085 0.82 TDP1 (0.36) TSHRTDP1
SCHEMBL141387 0.82 TSHR (0.41) MAPTTSHRTDP1
SCHEMBL4277441 0.80 TDP1 (0.39) TSHRTDP1
SCHEMBL1173040 0.80 TSHR (0.38) MAPTCACNA1BAPBA1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569327-B2 Curable polymer compound SHOWDA DENKO K.K. (JP) 2009-08-04 US disclosed
EP-1629046-B1 CURABLE POLYMER COMPOUND SHOWA DENKO KK (JP) 2008-05-14 EP disclosed
US-20070021571-A1 Curable polymer compound SHOWA DENKO K.K. (JP) 2007-01-25 US disclosed
US-7049350-B2 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2006-05-23 US disclosed
EP-1629046-A2 CURABLE POLYMER COMPOUND Showa Denko K.K. (JP) 2006-03-01 EP disclosed
WO-2004106431-A2 CURABLE POLYMER COMPOUND SHOWA DENKO K.K. (JP) 2004-12-09 WO disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
WO-2003010124-A1 POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND SHOWA DENKO K. K. (JP) 2003-02-06 WO disclosed