Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449417 | 1.00 | HCAR2 (0.41) | HCAR2MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL4449424 | 0.93 | HCAR2 (0.53) | HCAR2MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL7198717 | 0.93 | HCAR2 (0.53) | HCAR2MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL7196478 | 0.93 | HCAR2 (0.53) | HCAR2MAPTCACNA1BAPBA1TSHR | |
| SCHEMBL1886950 | 0.88 | TSHR (0.44) | MAPTCACNA1BAPBA1TSHRTDP1 | |
| SCHEMBL10482082 | 0.83 | TDP1 (0.37) | TSHRTDP1 | |
| SCHEMBL10482085 | 0.82 | TDP1 (0.36) | TSHRTDP1 | |
| SCHEMBL141387 | 0.82 | TSHR (0.41) | MAPTTSHRTDP1 | |
| SCHEMBL4277441 | 0.80 | TDP1 (0.39) | TSHRTDP1 | |
| SCHEMBL1173040 | 0.80 | TSHR (0.38) | MAPTCACNA1BAPBA1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176136-A1 | PROCESS FOR PRODUCING FUMARIC ESTER | Showa Denko K.K. (JP) | 2002-01-30 | — | — | EP | disclosed |
| US-20020002306-A1 | Method for producing fumaric acid esters | SHOWA DENKO K.K. (JP) | 2002-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002306-A1 | Method for producing fumaric acid esters | FH, ME1, ME3 | HCAR2 750/4885MAPT 1722/4885CACNA1B 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.