SCHEMBL4449478

SCHEMBL4449478

ClCc1c(Br)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PTPN1 P18031 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11436697 0.96 CA1 (0.30) CA1CA2PTPN1CA4CA6
SCHEMBL11146440 0.96 CA1 (0.33) CA1CA2PTPN1CA4CA6
SCHEMBL11349068 0.92 CA1 (0.32) CA1CA2PTPN1CA4CA6
SCHEMBL30595360 0.76
SCHEMBL21218775 0.76
SCHEMBL11520327 0.72
SCHEMBL258315 0.69 ALDH1A1 (0.33)
SCHEMBL332145 0.67 CA1 (0.35) CA1CA2PTPN1CA4CA6
SCHEMBL2037201 0.67 CA1 (0.59) CA1CA2PTPN1CA4CA6
SCHEMBL10495925 0.67 CA1 (0.32) CA1CA2PTPN1CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113174000-B Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2022-07-26 CN claimed
CN-113174000-A Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2021-07-27 CN claimed
CN-1989188-B Novel flame-retardant polystyrenes BROMINE COMPOUNDS LTD 2010-05-12 CN claimed
US-7585912-B2 Flame-retardant polystyrenes BROMINE COMPOUNDS LTD. (IL) 2009-09-08 US claimed
EP-1786853-B1 NOVEL FLAME-RETARDANT POLYSTYRENES BROMINE COMPOUNDS LTD (IL) 2009-04-15 EP claimed
JP-2008506829-A 2008-03-06 JP claimed
US-20070257241-A1 Novel Flame-Retardant Polystyrenes BROMINE COMPOUNDS LTD. (IL) 2007-11-08 US claimed
CN-1989188-A Novel flame-retardant polystyrenes BROMINE COMPOUNDS LTD (IL) 2007-06-27 CN claimed
EP-1786853-A1 NOVEL FLAME-RETARDANT POLYSTYRENES Bromine Compounds Ltd. (IL) 2007-05-23 EP claimed
WO-2006013554-A1 NOVEL FLAME-RETARDANT POLYSTYRENES BROMINE COMPOUNDS LTD. (IL) 2006-02-09 WO claimed
CN-113174000-B Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2022-07-26 CN disclosed
CN-113174000-A Preparation method of poly (pentabromobenzyl acrylate) with controllable molecular weight 潍坊鑫洋化工有限公司 2021-07-27 CN disclosed
US-9573878-B2 Process for the preparation of the monomer pentabromobenzyl acrylate and polymerization thereof BROMINE COMPOUNDS LTD. (IL) 2017-02-21 US disclosed
US-20160107979-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF BROMINE COMPOUNDS LTD. (IL) 2016-04-21 US disclosed
US-9255165-B2 Poly (pentabromobenzyl acrylate) and its properties BROMINE COMPOUNDS LTD. (IL) 2016-02-09 US disclosed
US-4211730-A HALOBROMOBENZYL ACRYLATE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed
US-4128709-A Acrylate-based polymers and their use as flameproofing agents DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4119612-A Polymeric and oligomeric formals DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4059618-A CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed
US-4059618-A CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160107979-A1 PROCESS FOR THE PREPARATION OF THE MONOMER PENTABROMOBENZYL ACRYLATE AND POLYMERIZATION THEREOF ACR, MMAB, ALKBH3 CA1 3134/4885CA2 3889/4885PTPN1 1800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.