Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Taurine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.82 |
| ▸ | BLM | P54132 | 4/20 | 0.82 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurine SCHEMBL27814625 | 0.92 | LMNA (0.78) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL30191395 | 0.91 | — | — | |
| Taurine SCHEMBL30179154 | 0.91 | — | — | |
| Taurine SCHEMBL23068 | 0.91 | — | — | |
| Taurine SCHEMBL42632 | 0.91 | BLM (1.00) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL3152449 | 0.89 | LMNA (0.74) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL1526984 | 0.89 | LMNA (0.74) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL17801096 | 0.89 | LMNA (0.74) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL22774725 | 0.89 | LMNA (0.74) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL9112233 | 0.88 | BLM (0.82) | LMNABLMSLC6A6CYP2C19APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005320-A1 | COMPOSITIONS COMPRISING AMINO ACID BICARBONATE AND METHODS OF USE THEREOF | GASPARI NUTRITION, INC. | 2009-01-01 | — | — | US | disclosed |