SCHEMBL4449757

SCHEMBL4449757

Clc1ccc(-c2c(Cl)cc(Cl)c(Cl)c2Cl)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 10/20 0.60
CYP1B1 Q16678 1/20 0.60
CYP3A4 P08684 1/20 0.43
MEN1 O00255 2/20 0.42
HTT P42858 2/20 0.42
KMT2A Q03164 2/20 0.42
IKBKB O14920 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
TP53 P04637 1/20 0.39
NOTUM Q6P988 1/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4450479 0.86 AHR (0.65) AHRCYP1B1CYP3A4MEN1HTT
SCHEMBL23827192 0.83 AHR (0.65) AHRCYP1B1CYP3A4MEN1HTT
SCHEMBL29776918 0.81 AHR (0.62) AHRCYP1B1CYP3A4MEN1HTT
SCHEMBL29351484 0.81 AHR (0.62) AHRCYP1B1CYP3A4MEN1HTT
SCHEMBL463759 0.81 AHR (0.62) AHRCYP1B1CYP3A4MEN1HTT
SCHEMBL463744 0.81 ESR2 (0.52) AHRCYP1B1CYP3A4MEN1HTT
SCHEMBL23827190 0.80 AHR (0.67) AHRCYP1B1CYP3A4
SCHEMBL4453629 0.79 AHR (0.56) AHRCYP1B1CYP3A4MEN1KMT2A
SCHEMBL4459758 0.78 AHR (0.65) AHRCYP1B1CYP3A4MEN1HTT
Polychlorinated Biphenyl 126 SCHEMBL308662 0.75 AHR (1.00) AHRCYP1B1CYP3A4MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-113607100-B Ultralight and ultraaccurate portable coordinate measuring machine SA08700334公司 2024-08-16 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-114761901-A Leakage characterization for electronic circuit temperature monitoring 国际商业机器公司 2022-07-15 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed