Polychlorinated Biphenyl 126

Polychlorinated Biphenyl 126

SCHEMBL308662

Clc1ccc(-c2cc(Cl)c(Cl)c(Cl)c2)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 10/20 1.00
CYP1B1 Q16678 1/20 1.00
TP53 P04637 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
KMO O15229 2/20 0.44
NOTUM Q6P988 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Polychlorinated Biphenyl 126 SCHEMBL6942325 1.00 AHR (1.00) AHRCYP1B1TP53NPC1RAB9A
Polychlorinated Biphenyl 126 SCHEMBL6535350 1.00 AHR (1.00) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL137915 0.88 AHR (1.00) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL29769221 0.88 AHR (1.00) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL8773697 0.84 AHR (0.71) AHRCYP1B1ALDH1A1CYP3A4TSHR
SCHEMBL2906064 0.82 AHR (0.67) AHRCYP1B1ALDH1A1CYP3A4TSHR
SCHEMBL29776914 0.81 AHR (0.74) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL4454434 0.81 AHR (0.74) AHRCYP1B1TP53NPC1RAB9A
SCHEMBL8773713 0.79 AHR (0.70) AHRCYP1B1NPC1RAB9AALDH1A1
SCHEMBL4450479 0.79 AHR (0.65) AHRCYP1B1TP53NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 897 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4414356-A2 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME Nissui Corporation (JP) 2024-08-14 EP claimed
EP-3971165-B1 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME NISSUI CORP (JP) 2024-08-07 EP claimed
CN-117571845-A Method for rapidly and efficiently detecting organic chlorine and polychlorinated biphenyl in soil simultaneously 济南市环境研究院(济南市黄河流域生态保护促进中心) 2024-02-20 CN claimed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN claimed
CN-113495108-B Method for simultaneously detecting 63 persistent organic pollutants in soil 生态环境部华南环境科学研究所 2023-07-28 CN claimed
CN-114014934-B Polychlorinated biphenyl monoclonal antibody and application thereof 江苏省农业科学院 2023-05-05 CN claimed
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US claimed
CN-112730559-B Preparation method and application of photoelectric aptamer sensor for detecting PCB72 山西大学 2022-07-19 CN claimed
EP-2851361-B1 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME NIPPON SUISAN KAISHA LTD (JP) 2021-11-24 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20110123624-A1 FORMULATIONS COMPRISING AMINOSTEROLS ENTERIN, INC. 2011-05-26 US claimed
WO-2011056650-A2 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS ZASLOFF MICHAEL (US) 2011-05-12 WO claimed
US-20110097303-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS ENTERIN, INC. 2011-04-28 US claimed
US-20100267829-A1 Pharmaceutical composition comprising low concentrations of environment pollutants PRONOVA BIOPHARMA NORGE 2010-10-21 US claimed
US-20100233281-A1 PROCESS FOR DECREASING ENVIRONMENTAL POLLUTANTS IN AN OIL OR A FAT. PRONOVA BIOPHARMA NORGE AS 2010-09-16 US claimed
US-6204005-B1 ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER ECOCHEM RESEARCH, INC. 2001-03-20 US claimed
EP-0859949-A4 PROCESS FOR EXTRACTING COMPOUNDS FROM SAMPLE MATRICES TRIANGLE LAB INC (US) 2000-03-29 EP claimed
US-5854010-A Bioassay for detecting 2,3,7,8-tetrachlorodibenzo-para-dioxin and TCDD-like compounds and novel recombinant cell line useful therefor XENOBIOTIC DETECTION SYSTEMS INTERNATIONAL, INC. 1998-12-29 US claimed
EP-0859949-A1 PROCESS FOR EXTRACTING COMPOUNDS FROM SAMPLE MATRICES Triangle Laboratories Inc. (US) 1998-08-26 EP claimed
WO-1997017601-A1 PROCESS FOR EXTRACTING COMPOUNDS FROM SAMPLE MATRICES TRIANGLE LABORATORIES, INC. (US) 1997-05-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123624-A1 FORMULATIONS COMPRISING AMINOSTEROLS HSD3B1, CYP17A1, HSD3B2 AHR 3660/4885CYP1B1 1267/4885TP53 1789/4885
US-20110097303-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS STING1, IFNG, TSLP AHR 2810/4885CYP1B1 3347/4885TP53 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.