SCHEMBL4459758

SCHEMBL4459758

Clc1cc(Cl)c(-c2ccc(Cl)c(Cl)c2)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.65
TP53 P04637 1/20 0.57
CYP1B1 Q16678 1/20 0.54
MEN1 O00255 2/20 0.46
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
IKBKB O14920 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
NOTUM Q6P988 1/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
ALOX12 P18054 1/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456561 0.82 AHR (0.62) AHRTP53CYP1B1MEN1HTT
SCHEMBL137915 0.80 AHR (1.00) AHRTP53CYP1B1MEN1HTT
SCHEMBL29769221 0.80 AHR (1.00) AHRTP53CYP1B1MEN1HTT
SCHEMBL23827192 0.79 AHR (0.65) AHRTP53CYP1B1MEN1HTT
SCHEMBL4454434 0.79 AHR (0.74) AHRTP53CYP1B1MEN1HTT
SCHEMBL29776914 0.79 AHR (0.74) AHRTP53CYP1B1MEN1HTT
SCHEMBL463716 0.78 HSD17B10 (0.62) AHRMEN1HTTKMT2AALDH1A1
SCHEMBL3018348 0.78 AHR (0.56) AHRTP53CYP1B1MEN1HTT
SCHEMBL4449757 0.78 AHR (0.60) AHRTP53CYP1B1MEN1HTT
SCHEMBL2936537 0.78 AHR (0.55) AHRTP53ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-0554956-B1 Thiazolylpyrroles having a fungicidal activity MINI RICERCA SCIENT TECNOLOG (IT) 1997-10-01 EP claimed
CN-108569395-B Unmanned aerial vehicle with pipeline structure 三星电子株式会社 2023-04-18 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed