SCHEMBL4449930

SCHEMBL4449930

CCCCC1(C)OC(=O)C(C)OC1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.30
HSD17B10 Q99714 1/20 0.30
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL252070 0.93 SIRT2 (0.36) CYP1A2PRKCA
SCHEMBL4453839 0.89
SCHEMBL1128661 0.82
SCHEMBL17151112 0.73 GAA (0.42)
SCHEMBL246419 0.72
SCHEMBL17154004 0.71 CNR2 (0.31)
SCHEMBL31634552 0.69 SIRT2 (0.31)
SCHEMBL9413704 0.69 ELANE (0.37)
SCHEMBL16138831 0.69 TP53 (0.31) CYP1A2
SCHEMBL3682174 0.69 TP53 (0.31) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9539332-B2 Plasticizers for coating compositions ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2017-01-10 US disclosed
US-20150150989-A1 Plasticizers For Coating Compositions ABBOTT CARDIOVASCULAR SYSTEMS (US) 2015-06-04 US disclosed
US-8980300-B2 Plasticizers for coating compositions ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2015-03-17 US disclosed
US-20090238854-A1 PLASTICIZERS FOR COATING COMPOSITIONS ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150150989-A1 Plasticizers For Coating Compositions PBDC1, CAD, PLAUR CYP1A2 3620/4885HSD17B10 2194/4885PRKCA 1229/4885
US-20090238854-A1 PLASTICIZERS FOR COATING COMPOSITIONS PBDC1, CAD, PLAUR CYP1A2 3583/4885HSD17B10 2208/4885PRKCA 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.