Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450000 | 1.00 | HCRTR1 (0.41) | HCRTR1HCRTR2CYP2D6CCR3MAPT | |
| SCHEMBL4449096 | 0.85 | ALDH1A1 (0.43) | HCRTR1HCRTR2MAPTALDH1A1PKM | |
| SCHEMBL13783959 | 0.85 | ALDH1A1 (0.43) | HCRTR1HCRTR2MAPTALDH1A1PKM | |
| SCHEMBL4449093 | 0.85 | ALDH1A1 (0.43) | HCRTR1HCRTR2MAPTALDH1A1PKM | |
| SCHEMBL4451883 | 0.84 | CASR (0.41) | HCRTR1HCRTR2CYP2D6CCR3MAPT | |
| SCHEMBL13783971 | 0.84 | CASR (0.41) | HCRTR1HCRTR2CYP2D6CCR3MAPT | |
| SCHEMBL4451072 | 0.84 | CASR (0.41) | HCRTR1HCRTR2CYP2D6CCR3MAPT | |
| SCHEMBL4323673 | 0.81 | CHRM3 (0.38) | CCR3ALDH1A1PKMGAAMEN1 | |
| SCHEMBL13783960 | 0.80 | NPC1 (0.41) | HCRTR1HCRTR2ALDH1A1PKMGAA | |
| SCHEMBL4455115 | 0.80 | ALDH1A1 (0.40) | MAPTALDH1A1PKMGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |