Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449096 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL13783959 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL4450002 | 0.85 | HCRTR1 (0.41) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL4450000 | 0.85 | HCRTR1 (0.41) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL4458269 | 0.82 | CCR3 (0.47) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL4458275 | 0.82 | CCR3 (0.47) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL13783977 | 0.82 | CCR3 (0.47) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL4455115 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL4455110 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL13783794 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ERAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |