SCHEMBL4450035

SCHEMBL4450035

Clc1ccc(-c2cc(Cl)cc(Cl)c2Cl)c(Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.61
ALDH1A1 P00352 4/20 0.50
TP53 P04637 1/20 0.46
S100A4 P26447 2/20 0.44
HSD11B1 P28845 1/20 0.44
TSHR P16473 3/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
CYP3A4 P08684 1/20 0.41
SCN9A Q15858 2/20 0.41
SCN2A Q99250 2/20 0.41
SCN3A Q9NY46 2/20 0.41
SCN10A Q9Y5Y9 2/20 0.41
SCN1A P35498 1/20 0.41
KCNH2 Q12809 1/20 0.41
SCN5A Q14524 1/20 0.41
PPOX P50336 1/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454535 0.86 TP53 (0.52) AHRALDH1A1TP53S100A4TSHR
SCHEMBL464507 0.84 AHR (0.64) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL29624840 0.84 AHR (0.64) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL2930780 0.84 ALDH1A1 (0.69) AHRALDH1A1TP53TSHRHSD17B10
SCHEMBL29355007 0.84 AHR (0.59) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL4456776 0.84 AHR (0.59) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL4459802 0.81 AHR (0.61) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL30336978 0.80 TP53 (0.57) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL4446831 0.80 TP53 (0.57) AHRALDH1A1TP53S100A4HSD11B1
SCHEMBL4450365 0.79 AHR (0.56) AHRALDH1A1TP53S100A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-108710189-B Lens driving motor, camera and mobile terminal device 上海比路电子股份有限公司 2024-08-16 CN disclosed
CN-108681025-B Lens driving motor, camera and mobile terminal device 上海比路电子股份有限公司 2024-08-16 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116300175-A Display module and spliced display screen 惠科股份有限公司 2023-06-23 CN disclosed
CN-115734469-A Circuit board and electronic equipment 华为技术有限公司 2023-03-03 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed