SCHEMBL464507

SCHEMBL464507

Clc1ccc(-c2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.64
TP53 P04637 2/20 0.61
HSD11B1 P28845 2/20 0.54
TSHR P16473 5/20 0.52
CYP3A4 P08684 3/20 0.52
HSD17B10 Q99714 2/20 0.52
S100A4 P26447 1/20 0.50
ALDH1A1 P00352 3/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
RAB9A P51151 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
TDP1 Q9NUW8 3/20 0.48
MAPK1 P28482 1/20 0.48
MAPT P10636 1/20 0.47
IDO1 P14902 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624840 1.00 AHR (0.64) AHRTP53HSD11B1TSHRCYP3A4
Polychlorinated Biphenyl 99 SCHEMBL4446838 0.89 AHR (0.63) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL30336978 0.89 TP53 (0.57) AHRTP53HSD11B1TSHRCYP3A4
Polychlorinated Biphenyl 99 SCHEMBL29624839 0.89 AHR (0.63) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL4446831 0.89 TP53 (0.57) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL29416163 0.87 AHR (0.52) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL665598 0.87 HSD17B10 (0.61) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL2934558 0.87 AHR (0.52) AHRTP53HSD11B1TSHRCYP3A4
SCHEMBL4452962 0.85 AHR (0.56) AHRTP53HSD11B1TSHRCYP3A4
Water SCHEMBL7522925 0.84 HSD17B10 (0.58) AHRTP53HSD11B1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-110153175-A 2,2` in a kind of cobalt ions catalysis permonosulphuric acid hydrogen salt degradation soil, the method for 4,4`- tetrachloro biphenyl 北京师范大学 2019-08-23 CN claimed
US-5110901-A Polythioethers PHILLIPS PETROLEUM COMPANY (US) 1992-05-05 US claimed
US-5077374-A Reacting sulfur and a diphenyl ether in a polyhaloaromatic sol vent using a Friedel-crafts catalyst to obtain a polyphenoxathiinylene sulfide; heat resistance; circuits; capacitors PHILLIPS PETROLEUM COMPANY (US) 1991-12-31 US claimed
US-12577376-B2 Molded articles with laser-formed pattern Celanese Interntaional Corporation (US) 2026-03-17 US disclosed
US-12552901-B2 Polyarylene sulfide production method KUREHA CORPORATION (JP) 2026-02-17 US disclosed
US-20260042903-A1 Laser Transmissive Polyarylene Sulfide Composition TICONA LLC (US) 2026-02-12 US disclosed
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide TICONA LLC (US) 2026-02-12 US disclosed
US-12509555-B2 Method for producing polyarylene sulfide KUREHA CORPORATION (JP) 2025-12-30 US disclosed
US-20250289956-A1 Polymer Composition With Improved Thermal Shock Resistance TICONA LLC 2025-09-18 US disclosed
US-20250250422-A1 Polyarylene Sulfide Composition With Improved Crystallization Properties TICONA LLC 2025-08-07 US disclosed
EP-2836555-B1 DYNAMICALLY VULCANIZED POLYARYLENE SULFIDE COMPOSITION TICONA LLC (US) 2025-07-09 EP disclosed
EP-0023313-A1 Process for preparing poly(arylene sulfides) BAYER AG (DE) 1981-02-04 EP disclosed
US-4246255-A Disposal of PCB ROCKWELL INTERNATIONAL CORPORATION (US) 1981-01-20 US disclosed
US-4116947-A FROM P-DIHALOBENZENE, POLYHALO AROMATIC COMPOUND, ALKALI METAL SULFIDE, N-ALKYL LACTAM AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-09-26 US disclosed
US-4089847-A Temperature programming in the production of arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1978-05-16 US disclosed
US-4064114-A Production of arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1977-12-20 US disclosed
US-4038261-A DIHALOBENZENE AND ALKALI METAL SULFIDE REACTANTS, A POLYHALO AROMATIC COMPOUND WHICH REDUCES MELT FLOW PHILLIPS PETROLEUM COMPANY (US) 1977-07-26 US disclosed
US-4038262-A PRODUCTION OF ARYLENE SULFIDE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1977-07-26 US disclosed
US-4025496-A Sequenced addition of components in poly(arylene sulfide) production PHILLIPS PETROLEUM COMPANY (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042903-A1 Laser Transmissive Polyarylene Sulfide Composition TRPC5, TRPC3, TRPC7 AHR 1309/4885TP53 2315/4885HSD11B1 2608/4885
US-12577376-B2 Molded articles with laser-formed pattern LAS1L, PIM2, YES1 AHR 2612/4885TP53 1627/4885HSD11B1 4742/4885
US-12509555-B2 Method for producing polyarylene sulfide AS3MT, ZW10, POLR2H AHR 273/4885TP53 2741/4885HSD11B1 93/4885
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide SLC39A3, SLC39A11, SLC39A14 AHR 416/4885TP53 4171/4885HSD11B1 2760/4885
US-12552901-B2 Polyarylene sulfide production method PEAK1, POLR2H, TDO2 AHR 41/4885TP53 2331/4885HSD11B1 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.