Marrubenol

Marrubenol

SCHEMBL4450048

C[C@@H]1C[C@@H](O)[C@H]2[C@@](C)(CO)CCC[C@]2(C)[C@@]1(O)CCc1ccoc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
USP2 O75604 1/20 0.44
CYP3A4 P08684 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NR1H4 Q96RI1 2/20 0.40
ERAP1 Q9NZ08 2/20 0.38
SULT1E1 P49888 1/20 0.34
PTPN1 P18031 1/20 0.31
CDC25A P30304 1/20 0.31
DUSP3 P51452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26472022 0.84 ALDH1A1 (0.53) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL4456739 0.83 ALDH1A1 (0.60) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL19766903 0.81 ALDH1A1 (0.51) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL26472020 0.77 ALDH1A1 (0.55) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL2784576 0.77 ALDH1A1 (0.55) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL17301626 0.77 ALDH1A1 (0.50) ALDH1A1MAPTUSP2CYP3A4HSD17B10
Rotundifuran SCHEMBL6233092 0.75 ALDH1A1 (0.56) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL13446720 0.74 ALDH1A1 (0.72) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL13446726 0.74 ALDH1A1 (0.72) ALDH1A1MAPTUSP2CYP3A4HSD17B10
SCHEMBL30525934 0.70 ALDH1A1 (0.47) ALDH1A1MAPTUSP2CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658087-A1 ANIMAL FEED ADDITIVE COMPOSITIONS AND METHODS OF USE PMI Nutrition, LLC (US) 2025-12-10 EP claimed
US-20240268416-A1 ANIMAL FEED ADDITIVE COMPOSITIONS AND METHODS OF USE PMI NUTRITION LLC (US) 2024-08-15 US claimed
WO-2024163291-A1 ANIMAL FEED ADDITIVE COMPOSITIONS AND METHODS OF USE PMI NUTRITION, LLC (US) 2024-08-08 WO claimed
EP-4408188-A1 FEED ADDITIVE COMPOSITIONS AND METHODS PMI Nutrition, LLC (US) 2024-08-07 EP claimed
CN-118175934-A Feed additive composition and method 普密艾营养有限公司 2024-06-11 CN claimed
US-20230381135-A1 COMPOSITION COMPRISING AT LEAST ONE LABDANE DITERPENE AND METHOD FOR MANUFACTURING SAME ELEONOR (BE) 2023-11-30 US claimed
EP-4228604-A1 COMPOSITION COMPRISING AT LEAST ONE LABDANE DITERPENE AND METHOD FOR MANUFACTURING SAME Tilman (BE) 2023-08-23 EP claimed
US-20230134934-A1 FEED ADDITIVE COMPOSITIONS AND METHODS PMI NUTRITION LLC (US) 2023-05-04 US claimed
WO-2023056376-A1 FEED ADDITIVE COMPOSITIONS AND METHODS PMI NUTRITION, LLC (US) 2023-04-06 WO claimed
WO-2022079090-A1 COMPOSITION COMPRISING AT LEAST ONE LABDANE DITERPENE AND METHOD FOR MANUFACTURING SAME TILMAN SA (BE) 2022-04-21 WO claimed
EP-1915166-B1 MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD PURANOX MEDICAL B V (NL) 2009-05-20 EP claimed
EP-4658087-A1 ANIMAL FEED ADDITIVE COMPOSITIONS AND METHODS OF USE PMI Nutrition, LLC (US) 2025-12-10 EP disclosed
US-20250098710-A1 FEED ADDITIVE COMPOSITIONS AND METHODS PMI NUTRITION LLC (US) 2025-03-27 US disclosed
US-12193457-B2 Feed additive compositions and methods PMI NUTRITION, LLC (US) 2025-01-14 US disclosed
US-20240268416-A1 ANIMAL FEED ADDITIVE COMPOSITIONS AND METHODS OF USE PMI NUTRITION LLC (US) 2024-08-15 US disclosed
EP-1915166-B1 MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD PURANOX MEDICAL B V (NL) 2009-05-20 EP disclosed
US-20080305192-A1 Marrubiin and Composition For Reducing Snoring, Package and Method PURANOX MEDICAL B.V. (NL) 2008-12-11 US disclosed
CN-101257913-A Marrubiin and composition for reducing snoring, package and method PURANOX MEDICAL B V (NL) 2008-09-03 CN disclosed
EP-1915166-A2 MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD Puranox Medical B.V. (NL) 2008-04-30 EP disclosed
WO-2007018432-A2 MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD PURANOX MEDICAL B.V. (NL) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305192-A1 Marrubiin and Composition For Reducing Snoring, Package and Method NISCH, UTRN, MTPN ALDH1A1 1660/4885MAPT 4300/4885USP2 3949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.