Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.35 |
| ▸ | CDC25A | P30304 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.34 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.34 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.34 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.34 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.34 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.34 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766903 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| Vitexilactone SCHEMBL4931755 | 0.79 | PPARG (0.46) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL26472022 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| Marrubenol SCHEMBL4450048 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| SCHEMBL26472020 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| SCHEMBL13446725 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| SCHEMBL13446726 | 0.71 | ALDH1A1 (0.72) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| SCHEMBL13446720 | 0.71 | ALDH1A1 (0.72) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| SCHEMBL28317029 | 0.69 | ALDH1A1 (0.48) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 | |
| SCHEMBL30525934 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTUSP2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131061-B1 | AGENT FOR LOWERING PROLACTIN | BIONORICA AG (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-20040138297-A1 | Agent for lowering prolactin | WUTTKE WOLFGANG (DE) | 2004-07-15 | — | — | US | disclosed |
| US-6635672-B1 | Labdane or celerodane type bicyclic diterpenes; menstrual cycle disorders | BIONORICA AG (DE) | 2003-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138297-A1 | Agent for lowering prolactin | PRLHR, ADCYAP1R1, GHRHR | ALDH1A1 619/4885MAPT 3267/4885USP2 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.