Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MARS1 | P56192 | 13/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225651 | 0.88 | SRD5A2 (0.62) | SRD5A2MARS1AHRCNR1DAGLA | |
| SCHEMBL2414197 | 0.79 | SRD5A2 (0.47) | SRD5A2MARS1AHRCNR1CNR2 | |
| SCHEMBL1639316 | 0.79 | KMT2A (0.46) | — | |
| SCHEMBL1637928 | 0.79 | CYP2A6 (0.52) | — | |
| SCHEMBL2933108 | 0.77 | AHR (0.67) | SRD5A2MARS1AHR | |
| SCHEMBL56865 | 0.77 | KMT2A (0.50) | — | |
| SCHEMBL444367 | 0.75 | SRD5A2 (0.90) | SRD5A2MARS1 | |
| SCHEMBL4300785 | 0.75 | SRD5A2 (0.68) | SRD5A2MARS1AHRCNR1 | |
| SCHEMBL30837198 | 0.74 | SRD5A2 (0.66) | SRD5A2MARS1AHRCNR1CNR2 | |
| SCHEMBL16492515 | 0.74 | SRD5A2 (0.66) | SRD5A2MARS1AHRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560597-B2 | 2′,4′-dichloro-biphenyl-4-yl-hydroxy-ketones and related compounds and their use as therapeutic agents | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2009-07-14 | — | — | US | disclosed |
| US-7560597-B2 | 2′,4′-dichloro-biphenyl-4-yl-hydroxy-ketones and related compounds and their use as therapeutic agents | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2009-07-14 | — | — | US | disclosed |
| US-7560597-B2 | 2′,4′-dichloro-biphenyl-4-yl-hydroxy-ketones and related compounds and their use as therapeutic agents | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2009-07-14 | — | — | US | disclosed |
| US-20080221220-A1 | 2',4'-DICHLORO-BIPHENYL-4-YL-HYDROXY-KETONES AND RELATED COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2008-09-11 | — | — | US | disclosed |
| US-20080221220-A1 | 2',4'-DICHLORO-BIPHENYL-4-YL-HYDROXY-KETONES AND RELATED COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221220-A1 | 2',4'-DICHLORO-BIPHENYL-4-YL-HYDROXY-KETONES AND RELATED COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | RORB, RORC, NR1H2 | SRD5A2 188/4885MARS1 4662/4885AHR 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.