SCHEMBL445035

SCHEMBL445035

COCCC[Si](OC)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ALDH1A1 P00352 3/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12532431 0.92 LMNA (0.39) LMNAALDH1A1GAATSHR
SCHEMBL11123386 0.90 LMNA (0.35) LMNAALDH1A1GAA
SCHEMBL4932454 0.89 LMNA (0.42) LMNAALDH1A1GAATSHR
SCHEMBL22806611 0.89 LMNA (0.42) LMNAALDH1A1GAATSHR
SCHEMBL16746517 0.89 LMNA (0.42) LMNAALDH1A1GAATSHR
SCHEMBL28379552 0.85 LMNA (0.35) LMNATSHR
SCHEMBL431419 0.85 LMNA (0.35) LMNATSHR
SCHEMBL17660486 0.85 LMNA (0.35) LMNATSHR
SCHEMBL13260411 0.83 LMNA (0.34) LMNA
SCHEMBL298549 0.82 LMNA (0.40) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 942 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122057451-A CO (carbon monoxide)2Preparation method of graded porous MOF nanofiber aerogel for trapping 东华大学 2026-05-19 CN claimed
CN-122037445-A Dampproof impact-resistant polyolefin elastomer for electronic detonator and preparation method thereof 无锡市伟达化工有限公司 2026-05-15 CN claimed
CN-118460074-B Preparation method of photoetching coating 长沙韶光芯材科技有限公司 2026-05-12 CN claimed
US-20260117376-A1 METHOD AND SYSTEM FOR FORMING A SILICON-CONTAINING LAYER AND STRUCTURE FORMED USING SAME ASM IP HOLDING BV (NL) 2026-04-30 US claimed
US-20250320601-A1 METHOD AND SYSTEM FOR FORMING A SILICON OXYCARBIDE LAYER AND STRUCTURE FORMED USING SAME ASM IP HOLDING BV (NL) 2025-10-16 US claimed
EP-4626596-A1 FLOW CELLS WITH PASSIVATION COMPONENTS Illumina, Inc. (US) 2025-10-08 EP claimed
US-12359312-B2 Method and system for forming a silicon oxycarbide layer and structure formed using same ASM IP HOLDING B.V. (NL) 2025-07-15 US claimed
CN-120032985-A Composite iron-nickel magnetic powder core and preparation method and application thereof 横店集团东磁股份有限公司 2025-05-23 CN claimed
US-12305281-B2 Method for forming metal silicon oxide and metal silicon oxynitride layers ASM IP HOLDING B.V. (NL) 2025-05-20 US claimed
CN-119955422-A High-adhesive-degree high-reliability ultraviolet light curing adhesive composition with high vehicle-gauge 上海汉司实业有限公司 2025-05-09 CN claimed
US-6537675-B1 Protective film of at least one inert silane, titanate or zirconate overlying the first side of the metal foil; and a metal sheet having a first side and a second side, the first side overlying the protective film GA-TEK, INC. 2003-03-25 US claimed
CN-1341683-A Polyacrylonitrile/inorganic composite material, its preparation method and application GUANGZHOU INST OF CHEMISTRY (CN) 2002-03-27 CN claimed
CN-1341682-A Modified methyl acrylic high polymer/inorganic composite material and its preparation method and application GUANGZHOU INST OF CHEMISTRY (CN) 2002-03-27 CN claimed
US-6299721-B1 CONTACTING FIRST SIDE OF METAL FOIL WITH SOLUTION COMPRISING HYDROCARBYLSILANE, WATER, ORGANIC SOLVENT AND TRIAZOLE COMPOUND TO FORM RESIN DUST RESISTANT FILM ON SURFACE OF METAL GOULD ELECTRONICS INCL 2001-10-09 US claimed
US-20010015257-A1 Coatings for improved resin dust resistance NIKKO MATERIALS USA, INC. 2001-08-23 US claimed
EP-1011299-A2 Coatings for improved resin dust resistance GA-TEK Inc. (US) 2000-06-21 EP claimed
CN-1256974-A Paint for improving resin stive property CAB TEC INC (US) 2000-06-21 CN claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
CN-1106977-A Metallic foil with adhesion promoting layer COULD ELECTRONICS INC (US) 1995-08-16 CN claimed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117376-A1 METHOD AND SYSTEM FOR FORMING A SILICON-CONTAINING LAYER AND STRUCTURE FORMED USING SAME NOXO1, NOX3, TIE1 LMNA 1776/4885ALDH1A1 4168/4885GAA 4620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.