Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593972 | 0.85 | NOTUM (0.44) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL28176768 | 0.84 | ADRB1 (0.49) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL12324599 | 0.83 | ADRB1 (0.51) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL27032901 | 0.83 | ADRB1 (0.51) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL15148004 | 0.83 | ADRB1 (0.51) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL24899325 | 0.83 | NOTUM (0.49) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL20956929 | 0.83 | NOTUM (0.49) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL12127775 | 0.82 | ALDH1A1 (0.43) | ADRB1ALDH1A1TSHRHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL27823517 | 0.82 | ADRB1 (0.50) | NOTUMADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL12125914 | 0.82 | NOTUM (0.44) | NOTUMADRB1USP2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616808-B1 | PROLYL ENDOPEPTIDASE PROBES | STANFORD RES INST INT (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-2616808-A2 | PROLYL ENDOPEPTIDASE PROBES | SRI International (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037044-A2 | PROLYL ENDOPEPTIDASE PROBES | SRI INTERNATIONAL (US) | 2012-03-22 | — | — | WO | disclosed |
| US-20120065103-A1 | Prolyl Endopeptidase Probes | SRI INTERNATIONAL | 2012-03-15 | — | — | US | disclosed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0525123-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | UPJOHN CO (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0525123-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. | UPJOHN CO (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065103-A1 | Prolyl Endopeptidase Probes | PREP, XPNPEP1, ANPEP | NOTUM 1014/4885ADRB1 3872/4885HTR3E 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.