SCHEMBL4450767

SCHEMBL4450767

CCCCC(Oc1cc[c]cc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.50
SLC7A5 Q01650 7/20 0.50
SLC6A2 P23975 3/20 0.42
SLC6A3 Q01959 3/20 0.42
HRH3 Q9Y5N1 2/20 0.42
NPC1 O15118 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C19 P33261 2/20 0.42
MTOR P42345 2/20 0.42
RAB9A P51151 2/20 0.42
KCNK2 O95069 2/20 0.42
KCNH2 Q12809 2/20 0.42
CACNA1C Q13936 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048337 0.94 SLC7A5 (0.51) SLC6A4SLC7A5SLC6A2SLC6A3HRH3
SCHEMBL27299983 0.89 SLC6A4 (0.62) SLC6A4SLC7A5SLC6A2SLC6A3HRH3
SCHEMBL5533459 0.83 SLC7A5 (0.55) SLC6A4SLC7A5HRH3NPC1CYP2D6
SCHEMBL4351195 0.81 SLC6A4 (0.57) SLC6A4SLC7A5SLC6A2SLC6A3HRH3
SCHEMBL27950265 0.78 SLC7A5 (0.50) SLC6A4SLC7A5MEN1KMT2A
SCHEMBL2776404 0.78 SLC7A5 (0.53) SLC6A4SLC7A5SLC6A2
SCHEMBL5171774 0.78 SLC6A4 (0.66) SLC6A4SLC7A5SLC6A2SLC6A3HRH3
SCHEMBL4754083 0.78 SLC6A4 (0.45) SLC6A4SLC7A5SLC6A2SLC6A3HRH3
SCHEMBL5958191 0.77 SLC6A4 (0.47) SLC6A4SLC7A5SLC6A2SLC6A3HRH3
SCHEMBL14302641 0.76 SLC7A5 (0.54) SLC6A4SLC7A5SLC6A2SLC6A3HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910454-B1 TRIETHANOLAMINE PERCHLORATO (TRIFLATO) METAL INNER COMPLEX COORDINATION POLYMERS AS ADDITIVES FOR SYNTHETIC POLYMERS CATENA ADDITIVES GMBH & CO KG (DE) 2009-10-21 EP disclosed