Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456865 | 0.81 | CYSLTR2 (0.42) | ALDH1A1LMNAPOLBRECQLHIF1A | |
| SCHEMBL13956429 | 0.79 | CYSLTR2 (0.39) | ALDH1A1LMNAPOLBRECQLHIF1A | |
| SCHEMBL4450812 | 0.78 | CA2 (0.35) | ALDH1A1LMNAPOLBRECQLHIF1A | |
| SCHEMBL2305004 | 0.76 | TYR (0.46) | ALDH1A1LMNAPOLBHIF1ATDP1 | |
| SCHEMBL4453277 | 0.73 | LTB4R (0.47) | — | |
| SCHEMBL13956434 | 0.73 | LTB4R (0.47) | — | |
| SCHEMBL4445395 | 0.72 | SCD (0.40) | ALDH1A1LMNAPOLBRECQLHIF1A | |
| SCHEMBL4460092 | 0.72 | S1PR1 (0.38) | ALDH1A1LMNAPOLBRECQLHIF1A | |
| SCHEMBL4450768 | 0.71 | LTB4R (0.49) | — | |
| SCHEMBL13956465 | 0.70 | TSHR (0.56) | ALDH1A1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |