Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.46 |
| ▸ | GALR3 | O60755 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450883 | 0.81 | NR2F2 (0.47) | RAB9ANR2F2GALR3NPC1KCNA3 | |
| SCHEMBL17737440 | 0.72 | P2RX7 (0.56) | KMT2ACASP1CASP7KDM4ELMNA | |
| SCHEMBL14193918 | 0.71 | MEN1 (0.52) | KMT2AKDM4EMAPT | |
| SCHEMBL7344375 | 0.71 | KDM4E (0.67) | RAB9ANR2F2KCNA3NR3C1CASP1 | |
| SCHEMBL5998660 | 0.70 | KDM4E (0.50) | RAB9ANR2F2KCNA3KMT2AGRIN1 | |
| SCHEMBL7870247 | 0.70 | KCNA3 (0.52) | RAB9ANR2F2GALR3KCNA3NR3C1 | |
| SCHEMBL367358 | 0.70 | MRGPRX4 (0.54) | RAB9ANR2F2KCNA3KMT2AKDM4E | |
| SCHEMBL11144866 | 0.70 | KCNA3 (0.61) | RAB9ANR2F2KCNA3NR3C1KDM4E | |
| SCHEMBL13788236 | 0.70 | KCNA3 (0.55) | RAB9ANR2F2KCNA3KMT2ANR3C1 | |
| SCHEMBL5445170 | 0.69 | KCNA3 (0.65) | RAB9ANR2F2KCNA3IKBKBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | disclosed |