Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17134667 | 0.83 | GAA (0.56) | MMP8GAAMGAMSIMGAM2 | |
| SCHEMBL7347653 | 0.82 | EGLN1 (0.37) | EGLN1MMP8GAAMGAMSI | |
| Malonic Acid SCHEMBL28187205 | 0.82 | ALDH1A1 (0.39) | EGLN1MMP8GAAMGAMSI | |
| SCHEMBL3142804 | 0.80 | SOAT1 (0.44) | EGLN1MMP8GAAMGAMSI | |
| SCHEMBL7684983 | 0.80 | LDHA (0.40) | TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL663775 | 0.80 | ALDH1A1 (0.46) | MMP8GAAMGAMSIMGAM2 | |
| SCHEMBL230068 | 0.79 | ALDH1A1 (0.50) | MMP8GAAMGAMSIMGAM2 | |
| Malonic Acid SCHEMBL28179527 | 0.78 | EGLN1 (0.37) | EGLN1MMP8GAATDP1ALDH1A1 | |
| Dimethylamine SCHEMBL15710606 | 0.78 | GAA (0.46) | MMP8GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL9430104 | 0.78 | ALDH1A1 (0.43) | MMP8GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56015279-A | — | — | None | — | — | JP | disclosed |
| US-8834643-B2 | Method and composition for cleaning objects | BUBBLES AND BEYOND GMBH (DE) | 2014-09-16 | — | — | US | disclosed |
| WO-2013113319-A1 | PROCESS FOR THE PREPARATION OF STRONTIUM RANELATE, INTERMEDIATE OR HYDRATES THEREOF | PHARMATHEN S.A. (GR) | 2013-08-08 | — | — | WO | disclosed |
| US-20120085371-A1 | METHOD AND COMPOSITION FOR CLEANING OBJECTS | BUBBLES AND BEYOND GMBH (DE) | 2012-04-12 | — | — | US | disclosed |
| CN-102387787-A | External preparation | BUBBLES AND BEYOND GMBH | 2012-03-21 | — | — | CN | disclosed |
| US-20120064011-A1 | PREPARATION FOR EXTERNAL APPLICATION | BUBBLES AND BEYOND GMBH (DE) | 2012-03-15 | — | — | US | disclosed |
| US-7964640-B2 | Oligomers of straight-chain and unbranched fatty acids and drugs containing these | PLT PATENT & LICENSE TRADING LTD. (GB) | 2011-06-21 | — | — | US | disclosed |
| US-7087614-B2 | Pyrimidine inhibitors of phosphodiesterase (PDE) 7 | BRISTOL-MYERS SQUIBB CO. (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1397142-A4 | PYRIMIDINE INHIBITORS OF PHOSPHODIESTERASE (PDE) 7 | BRISTOL MYERS SQUIBB CO (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1397142-A2 | PYRIMIDINE INHIBITORS OF PHOSPHODIESTERASE (PDE) 7 | Bristol-Myers Squibb Company (US) | 2004-03-17 | — | — | EP | disclosed |
| US-20030162802-A1 | Pyrimidine inhibitors of phosphodiesterase (PDE) 7 | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-28 | — | — | US | disclosed |
| WO-2002102313-A2 | PYRIMIDINE INHIBITORS OF PHOSPHODIESTERASE (PDE) 7 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |
| US-6034099-A | Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones | CELL PATHWAYS, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| JP-S5615279-A | NOVEL, LACTONE OF OCTANOIC ACIDS | SHIONO KORYO KK | 1981-02-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162802-A1 | Pyrimidine inhibitors of phosphodiesterase (PDE) 7 | PDE7A, PDE7B, PDE3A | EGLN1 1934/4885MMP8 794/4885GAA 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.