Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.69 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 3/20 | 0.55 |
| ▸ | CTSG | P08311 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307028 | 0.93 | SLC12A2 (0.67) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL7027470 | 0.92 | SLC12A2 (0.66) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL7027475 | 0.92 | SLC12A2 (0.66) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL4447511 | 0.92 | SLC12A2 (0.66) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL4455398 | 0.85 | KMT2A (0.56) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL17068754 | 0.83 | L3MBTL1 (1.00) | L3MBTL1KMT2AMAPK1PTGDR2MEN1 | |
| SCHEMBL7035111 | 0.81 | PTGDR2 (0.69) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL7028807 | 0.80 | SLC12A2 (0.51) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL4447514 | 0.80 | HPGD (0.58) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD | |
| SCHEMBL4452536 | 0.80 | CMA1 (0.56) | L3MBTL1KMT2ASLC12A2SLC12A5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054319-A1 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders | MICROBIA, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2006102069-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND GASTROINTESTINAL DISORDERS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20030083315-A1 | Human chymase inhibitors | TEIJIN LIMITED (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1167360-A9 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1167360-A1 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | CMA1, CTRL, CPA4 | L3MBTL1 1943/4885KMT2A 2450/4885SLC12A2 604/4885 |
| US-20090054319-A1 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders | PTGIS, PTGIR, GRPR | L3MBTL1 4400/4885KMT2A 4822/4885SLC12A2 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.