SCHEMBL4451205

SCHEMBL4451205

CC(OP(O)O)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.36
SLC6A4 P31645 1/20 0.36
RIPK1 Q13546 2/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2C P18825 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
LMNA P02545 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
AOC3 Q16853 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451203 0.85 MAPK1 (0.39) ALDH1A1ALOX15MAPK1SLC6A4RIPK1
SCHEMBL3490274 0.84 AOC3 (0.42) ALDH1A1ALOX15MAPK1SLC6A4RIPK1
SCHEMBL11770121 0.79 SLC6A4 (0.39) ALDH1A1SLC6A4RIPK1ADRA2AADRA2C
SCHEMBL29157951 0.75 ALDH1A1 (0.38) ALDH1A1ALOX15MAPK1SLC6A4RIPK1
SCHEMBL4448595 0.75 LMNA (0.35) ALDH1A1ESR1CYP3A4CNR1CNR2
SCHEMBL4459729 0.73 ALDH1A1 (0.35) ALDH1A1ALOX15MAPK1SLC6A4ADRA2A
SCHEMBL6809764 0.72 ALDH1A1 (0.46) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL18544240 0.72 ALDH1A1 (0.58) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL9494144 0.69 CYP2D6 (0.41) ALDH1A1ALOX15MAPK1ESR1ESR2
SCHEMBL18544226 0.69 CYP2D6 (0.41) ALDH1A1ALOX15MAPK1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed